List of substrates found:


Substrate: C-ets-1 protein (C-ets-1 protein)
Seq-ID: P14921 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-16586   DAXX_HUMAN
MINT-5207365   ANDR_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
RNA polymerase II transcription factor activity,
transcription factor binding,
sequence-specific DNA binding transcription factor activity,
protein binding		 nucleus transcription from RNA polymerase II promoter,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of transcription,
transcription,
cell motility,
negative regulation of cell proliferation,
positive regulation of cellular component movement,
immune response,
PML body organization,
positive regulation of erythrocyte differentiation,
response to antibiotic,
induction of apoptosis,
negative regulation of cell cycle
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 38 DMECADVPLLTPSSKEMMSQA MAPK7 12048211
LTP
0.70
 MOD_ProDKin_1
 - -
0.37
 --

Substrate: Connexin 43 (Intercellular channel)
Seq-ID: P08050 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
MINT-1791070   ZO1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
gap junction channel activity,
PDZ domain binding		 connexon complex,
Golgi-associated vesicle membrane,
early endosome,
integral to plasma membrane,
lysosome,
fascia adherens,
mitochondrial outer membrane,
endoplasmic reticulum membrane,
multivesicular body,
membrane raft		 positive regulation of protein catabolic process,
ATP transport,
response to pH,
negative regulation of cell proliferation,
apoptosis,
vascular transport,
gap junction assembly,
protein oligomerization,
cell-cell signaling,
neuron projection morphogenesis,
regulation of calcium ion transport,
response to peptide hormone stimulus
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 255 DPYHATTGPLSPSKDCGSPKY MAPK7 12637502
LTP
0.22
 MOD_ProDKin_1
 - -
0.40
 --

Substrate: MAP2K5 (Serine/threonine kinase)
Seq-ID: Q13163 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-48511   M3K3_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
metal ion binding,
ATP binding,
protein tyrosine kinase activity,
protein binding
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 129 GLKVNTRAGPSQHSSPAVSDS MAPK7 12628002
LTP
0.19
 - -
0.60
 - medium
S 137 GPSQHSSPAVSDSLPSNSLKK MAPK7 12628002
LTP
0.71
 - -
0.62
 - medium
S 142 SSPAVSDSLPSNSLKKSSAEL MAPK7 12628002
LTP
0.19
 - -
0.48
 - medium
S 149 SLPSNSLKKSSAELKKILANG MAPK7 12628002
LTP
0.08
 - -
0.37
 - medium

Substrate: Myocyte-specific enhancer factor 2A (Transcription factor)
Seq-ID: Q02078 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-49703   HDAC4_HUMAN
MINT-3380349   SUMO1_HUMAN
MINT-7973732   DLG4_RAT
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
sequence-specific DNA binding transcription factor activity		 nucleoplasm nervous system development,
transcription,
apoptosis,
muscle organ development,
regulation of transcription, DNA-dependent,
cell differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 312 SSSQATQPLATPVVSVTTPSL MAPK7 9858528
LTP
1.00
 MOD_ProDKin_1
 - -
0.70
 - medium
T 319 PLATPVVSVTTPSLPPQGLVY MAPK7 9858528
LTP
1.00
 MOD_ProDKin_1
 - -
0.56
 - medium
S 355 ADLSALQGFNSPGMLSLGQVS MAPK7 10849446
LTP
1.00
 MOD_ProDKin_1
 - -
0.57
 - medium

Substrate: Myocyte-specific enhancer factor 2C (Myocyte-specific enhancer factor 2C)
Seq-ID: Q06413 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
MINT-49706   HDAC4_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
RNA polymerase II transcription factor activity,
sequence-specific DNA binding transcription factor activity,
protein binding		 nuclear speck negative regulation of gene-specific transcription from RNA polymerase II promoter,
nervous system development,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
transcription,
apoptosis,
positive regulation of survival gene product expression,
muscle organ development,
cell differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 387 SSNLSLPSTQSLNIKSEPVSP MAPK7 9384584
LTP
0.14
 - -
0.74
 --

Substrate: Myocyte-specific enhancer factor 2D (Transcription factor)
Seq-ID: Q63943 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-19666   HDAC5_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
transcription activator activity,
sequence-specific DNA binding transcription factor activity		 nucleus nervous system development,
transcription,
apoptosis,
osteoblast differentiation,
endochondral ossification,
regulation of transcription, DNA-dependent,
chondrocyte differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 180 TSSLTDPRLLSPQQPALQRNS MAPK7 10849446
LTP
0.87
 MOD_ProDKin_1
 - -
0.78
 - medium

Substrate: Serine/threonine-protein kinase Sgk1 (Serine/threonine kinase)
Seq-ID: O00141 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-56642   CREB1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
ATP binding,
protein binding		 plasma membrane,
nucleus,
endoplasmic reticulum		 protein amino acid phosphorylation,
response to stress,
apoptosis,
sodium ion transport
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 78 LMNANPSPPPSPSQQINLGPS MAPK7 11254654
LTP
0.70
 MOD_ProDKin_1
 - -
0.81
 --

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