a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	Retinoblastoma-associated protein HEC (Cell cycle control protein)
Seq-ID:	O14777 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	MINT-63076   TM1L1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein binding Ndc80 complex, outer kinetochore of condensed nuclear chromosome cell division, mitotic sister chromatid segregation, phosphoinositide-mediated signaling, mitotic spindle organization, establishment of mitotic spindle orientation, attachment of spindle microtubules to kinetochore
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	165	FKDLGYPFALSKSSMYTVGAP	NEK2	12386167	LTP	1.00		-	Ndc80_HEC	0.09	2IGP	42.62%

Substrate:	Serine/threonine protein phosphatase PP1-gamma catalytic subunit (Protein phosphatase)
Seq-ID:	P36873 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-48225   NEMO_HUMAN MINT-48501   M3K3_HUMAN MINT-3374798   PP14B_HUMAN MINT-7235594   ASPP2_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein kinase binding, metal ion binding, protein serine/threonine phosphatase activity condensed chromosome kinetochore, cytoplasm, MLL5-L complex, nucleolus, nuclear speck cell division, cell cycle, glycogen metabolic process
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	307	KPAEKKKPNATRPVTPPRGMI	NEK2	10880350	LTP	0.06		-	-	0.73	-	medium
T	318	RPVTPPRGMITKQAKK	NEK2	10880350	LTP	0.06		-	-	0.66	-	medium