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Substrate: PDGF-R alpha (Receptor tyrosine kinase)
Seq-ID: P16234 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
platelet-derived growth factor alpha-receptor activity,
vascular endothelial growth factor receptor activity,
platelet-derived growth factor binding,
protein homodimerization activity,
platelet-derived growth factor receptor binding,
ATP binding		 integral to plasma membrane positive regulation of DNA replication,
positive regulation of fibroblast proliferation,
cell activation,
positive regulation of cell migration,
protein amino acid autophosphorylation,
peptidyl-tyrosine phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 754 PMLERKEVSKYSDIQRSLYDR PDGFR_alpha 7523122
LTP
0.27
 PTPN11 SH2 TyrKc
0.29
 - medium
Y 762 SKYSDIQRSLYDRPASYKKKS PDGFR_alpha 9546424
LTP
1.00
 CRKL SH2;
CRK SH2		 TyrKc
0.29
 - medium
Y 988 ARMRVDSDNAYIGVTYKNEED PDGFR_alpha 7535778
LTP
0.12
 PLCG1 SH2 -
0.41
 - medium
Y 1018 DEQRLSADSGYIIPLPDIDPV PDGFR_alpha 7535778
LTP
1.00
 PLCG1 SH2 -
0.49
 - medium

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