a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	PDGF-R beta (Beta platelet-derived growth factor receptor)
Seq-ID:	P09619 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-2832596   NHRF2_HUMAN MINT-2832984   PTEN_HUMAN MINT-2833042   NHRF1_HUMAN MINT-6762380   PTN1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process vascular endothelial growth factor receptor activity, platelet-derived growth factor binding, platelet activating factor receptor activity, platelet-derived growth factor receptor binding, ATP binding, platelet-derived growth factor beta-receptor activity integral to plasma membrane positive regulation of cell proliferation, positive regulation of cell migration, protein amino acid autophosphorylation, peptidyl-tyrosine phosphorylation, cell chemotaxis
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	751	MDMSKDESVDYVPMLDMKGDV	PDGFR_group	8195171	LTP	1.00		Fyn SH2; NCK SH2; PIK3R1 SH2; PIK3R2 SH2; PLCG1 SH2; RASA_group SH2; SHC1 SH2; SHC_group SH2; Src SH2	TyrKc	0.29	-	medium
Y	857	LARDIMRDSNYISKGSTFLPL	PDGFR_group	10821867	LTP	1.00		Fyn SH2; RASA_group SH2; Src SH2; YES1 SH2	TyrKc	0.08	-	medium
Y	857	LARDIMRDSNYISKGSTFLPL	PDGFR_group	2550144	LTP	1.00		Fyn SH2; RASA_group SH2; Src SH2; YES1 SH2	TyrKc	0.08	-	medium

Substrate:	Ras GTPase-activating protein 1 (Ras p21 activator protein (GAP))
Seq-ID:	P20936 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-74708   ERBB3_HUMAN MINT-74709   ERBB4_HUMAN MINT-74711   EGFR_HUMAN MINT-74712   ERBB2_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process potassium channel inhibitor activity, Ras GTPase activator activity, glycoprotein binding, GTPase binding, receptor binding cytoplasm intracellular signaling pathway, cytokinesis, regulation of actin filament polymerization, positive regulation of anti-apoptosis, regulation of cell shape, signal transduction, negative regulation of cell-matrix adhesion, vasculogenesis, negative regulation of neuron apoptosis, regulation of small GTPase mediated signal transduction, regulation of RNA metabolic process, embryo development
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	460	LNDTVDGKEIYNTIRRKTKDA	PDGFR_group	1850098	LTP	1.00		Lck SH2; Src SH2	-	0.31	-	low

Substrate:	SH2-B beta signaling protein (Unclassified)
Seq-ID:	ENSP00000352232 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	MINT-74717   EGFR_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process signal transducer activity cytoplasm, nucleus, membrane
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	439	ESNDRLSQGAYGGLSDRPSAS	PDGFR_group	12551917	LTP	0.10		-	-	0.71	-	medium