Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

133kDa myosin-binding subunit of smooth muscle myosin phosphatase
DRP-2
Erzin
Insulin receptor substrate 1
Moesin

Substrate:

133kDa myosin-binding subunit of smooth muscle myosin phosphatase (Unclassified)

Seq-ID:

ENSGALP00000016789 [Gallus gallus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein binding	cytoplasm

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	695	SRQARQSRRSTQGVTLTDLQE	ROCK2	11226254	LTP	1.00		-	-	0.80	-	medium

Substrate:

DRP-2 (Cytoskeletal associated protein)

Seq-ID:

Q16555 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6826109 RK_BOVIN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
dihydropyrimidinase activity, protein binding	microtubule cytoskeleton	signal transduction, nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	555	QIDDNIPRRTTQRIVAPPGGR	ROCK2	10818093	LTP	0.21		-	-	0.74	-	medium

Substrate:

Erzin (Connection of cytoscheletro structure to plasma membrane)

Seq-ID:

P26040 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-4085294 TNR6_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
cell adhesion molecule binding, actin filament binding	uropod, actin filament, microtubule basal body, ruffle membrane, microvillus membrane, extrinsic to membrane, apical plasma membrane, cell cortex	establishment or maintenance of apical/basal cell polarity, regulation of cell shape, actin filament bundle assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	567	NMRQGRDKYKTLRQIRQGNTK	ROCK2	9456324	LTP	0.95		-	ERM	0.75	-	medium

Substrate:

Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.)

Seq-ID:

P35569 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-58476   NUCL_MOUSE
MINT-6381887   P85A_MOUSE
MINT-6793439   PTN1_HUMAN
MINT-6794075   INSR_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphoinositide 3-kinase binding, insulin-like growth factor receptor binding, insulin receptor binding, SH2 domain binding	microsome, cytosol, nucleus	positive regulation of mesenchymal cell proliferation, positive regulation of cell migration, protein kinase B signaling cascade, mammary gland development, insulin receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	632	RKGNGDYMPMSPKSVSAPQQI	ROCK2	16098829	LTP	1.00		-	-	0.79	-	-
S	635	NGDYMPMSPKSVSAPQQIINP	ROCK2	16098829	LTP	1.00		-	-	0.72	-	-

Substrate:

Moesin (Adapter molecule)

Seq-ID:

P26041 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
	uropod, cytoplasm, basolateral plasma membrane, cytoskeleton, microvillus membrane, extrinsic to membrane, apical plasma membrane

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	558	NMRLGRDKYKTLRQIRQGNTK	ROCK2	9856983	LTP	0.98		-	ERM	0.70	-	medium
T	558	NMRLGRDKYKTLRQIRQGNTK	ROCK2	9456324	LTP	0.98		-	ERM	0.70	-	medium