a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	Histone H2A.c/d/i/n/p (histone H2A.1 (from PhosphoBase))
Seq-ID:	P0C0S8 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-3296701   1433Z_HUMAN MINT-3973898   RYBP_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process DNA binding, enzyme binding nucleus, nucleosome nucleosome assembly
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	2	MSGRGKQGGKAR	RSK-5	15010469	LTP	0.00		-	-	0.52	-	medium

Substrate:	p65 (Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit), RelA)
Seq-ID:	Q04206 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-50016   IKBA_MOUSE MINT-50017   IKBB_MOUSE MINT-50025   KAPCA_HUMAN MINT-50073   KS6A5_HUMAN MINT-50084   KPCZ_HUMAN MINT-50090   CSK21_HUMAN MINT-50107   IKKA_HUMAN MINT-50167   IKKB_HUMAN MINT-50171   HDAC1_HUMAN MINT-50175   KAT2B_HUMAN MINT-50178   EP300_HUMAN MINT-50179   HDAC3_HUMAN MINT-58638   NCF1_HUMAN MINT-62399   TF2B_HUMAN MINT-2834593   NCOA3_HUMAN MINT-6166971   OGT1_HUMAN MINT-7235700   ASPP2_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process transcription repressor activity, transcription repressor binding, identical protein binding, protein kinase binding, ubiquitin protein ligase binding, transcription activator binding, transcription activator activity, RNA polymerase II transcription factor activity, enhancer binding, promoter binding, protein N-terminus binding, phosphate binding, NF-kappaB binding cytosol, transcription factor complex transcription, positive regulation of I-kappaB kinase/NF-kappaB cascade, cytokine-mediated signaling pathway, anti-apoptosis, defense response to virus, membrane protein intracellular domain proteolysis, cellular defense response, inflammatory response, nucleotide-binding oligomerization domain containing 2 signaling pathway, response to interleukin-1, interspecies interaction between organisms, positive regulation of NF-kappaB transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, response to UV-B, negative regulation of gene-specific transcription
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	276	VRVSMQLRRPSDRELSEPMEF	RSK-5	12628924	LTP	1.00		-	IPT	0.58	1MY7	67.21%

Substrate:	p65 (Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit), RelA)
Seq-ID:	Q04207 [Mus musculus]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-19530   IKBA_MOUSE MINT-19560   IKBB_MOUSE MINT-7288484   UBIQ_MOUSE MINT-7288511   CUL2_MOUSE
GO-Terms:	[show] Molecular Function Cellular Component Biological Process transcription activator activity, RNA polymerase II transcription factor activity, enhancer binding, chromatin binding cytosol transcription, organ morphogenesis, negative regulation of protein catabolic process, hair follicle development, liver development, positive regulation of interleukin-12 biosynthetic process, response to muramyl dipeptide
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	276	VRVSMQLRRPSDRELSEPMEF	RSK-5	16135789	LTP	1.00	MOD_PKA_1	-	IPT	0.57	1MY7	67.21%

Substrate:	RPS6KA5 (serine/threonine kinase)
Seq-ID:	O75582 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-50073   TF65_HUMAN MINT-6771456   GCR_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process magnesium ion binding, protein serine/threonine kinase activity, ATP binding, protein binding cytoplasm, nucleoplasm response to chemical stimulus, response to stress, epidermal growth factor receptor signaling pathway, regulation of transcription, DNA-dependent, histone phosphorylation, response to external stimulus, intracellular protein kinase cascade
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	212	FVADETERAYSFCGTIEYMAP	RSK-5	15568999	LTP	1.00		-	S_TKc	0.15	1VZO	62.25%
S	376	QSSEKLFQGYSFVAPSILFKR	RSK-5	15568999	LTP	0.99		-	S_TK_X	0.12	-	-
S	381	LFQGYSFVAPSILFKRNAAVI	RSK-5	15568999	LTP	1.00		-	Pkinase_C	0.08	-	-
S	750	LAKRRKMKKTSTSTETRSSSS	RSK-5	15568999	LTP	1.00		-	-	0.80	-	-
S	752	KRRKMKKTSTSTETRSSSSES	RSK-5	15568999	LTP	0.38		-	-	0.81	-	-
S	758	KTSTSTETRSSSSESSHSSSS	RSK-5	15568999	LTP	1.00		-	-	0.84	-	-