List of substrates found:


Substrate: APBB1 (beta-amyloid binding, histone acetyltransferase binding)
Seq-ID: P46933 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-49648   A4_HUMAN
MINT-49663   ABL1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
beta-amyloid binding,
transcription factor binding,
protein complex binding		 plasma membrane,
dendritic spine,
presynaptic membrane,
lamellipodium,
nucleus,
perinuclear region of cytoplasm,
protein complex,
growth cone,
postsynaptic membrane		 negative regulation of thymidylate synthase biosynthetic process,
transcription,
histone H4 acetylation,
apoptosis,
negative regulation of cell growth,
cell cycle arrest,
negative regulation of S phase of mitotic cell cycle,
positive regulation of apoptosis,
positive regulation of protein secretion,
positive regulation of DNA repair,
response to iron ion,
double-strand break repair,
positive regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 611 VLGECRVRFLSFLAVGRDVHT SGK_group 18304449
LTP
1.00
 - PTB
0.03
 3DXC 38.52%

Substrate: ATP-sensitive inward rectifier potassium channel 1 (Inward rectifier potassium channel activity)
Seq-ID: O88335 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
inward rectifier potassium channel activity,
ATP binding,
protein binding		 integral to membrane
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 25 GRSRQRARLVSKDGRCNIEFG SGK_group 12684516
LTP
0.30
 - IRK
0.14
 - low

Substrate: ATP-sensitive inward rectifier potassium channel 1 (Inward rectifier potassium channel activity)
Seq-ID: P48048 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
inward rectifier potassium channel activity,
ATP binding		 voltage-gated potassium channel complex excretion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 44 GHSRQRARLVSKDGRCNIEFG SGK_group 12878206
LTP
0.30
 - IRK
0.14
 - low

Substrate: B-Raf (B-Raf proto-oncogene serine/threonine-protein kinase)
Seq-ID: P15056 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-50344   1433B_HUMAN
MINT-50372   1433T_HUMAN
MINT-2833162   KPCA_HUMAN
MINT-2833238   KPCE_HUMAN
MINT-2833314   KS6A2_HUMAN
MINT-3295552   1433Z_HUMAN
MINT-3374124   M3K1_HUMAN
MINT-3975375   1433S_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
metal ion binding,
ATP binding		 cytoplasm,
nucleus		 protein amino acid phosphorylation,
organ morphogenesis,
anti-apoptosis,
small GTPase mediated signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 365 NQFGQRDRSSSAPNVHINTIE SGK_group 11410590
LTP
1.00
 MOD_PKB_1
 YWHAB 14-3-3 -
0.74
 --

Substrate: Calcium-regulated heat stable protein 1 (Calcium binding protein)
Seq-ID: Q9Y2V2 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-65805   STC2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
DNA binding,
phosphatase binding		 cytoplasm intracellular signaling pathway,
regulation of transcription, DNA-dependent
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 52 PLPTRRTRTFSATVRASQGPV SGK_group 15910284
LTP
1.00
 - -
0.65
 - medium

Substrate: CREB (cAMP response element binding protein (CREB).)
Seq-ID: P16220 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-16217   BRCA1_HUMAN
MINT-56642   SGK1_HUMAN
MINT-63231   RECQ5_HUMAN
MINT-63483   VIME_HUMAN
MINT-63485   CHD3_HUMAN
MINT-4979977   CBP_HUMAN
MINT-5209851   EP300_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein dimerization activity,
transcription cofactor activity		 protein amino acid phosphorylation,
signal transduction,
interspecies interaction between organisms,
response to organic substance
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 133 KRREILSRRPSYRKILNDLSS SGK_group 15733869
LTP
1.00
 - pKID
0.54
 - low

Substrate: E3 ubiquitin-protein ligase Nedd-4-like protein (Ubiquitin-protein ligase activity)
Seq-ID: Q96PU5 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-61615   SMAD2_HUMAN
MINT-63860   GDIR1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sodium channel regulator activity,
protein binding,
ubiquitin-protein ligase activity		 cytoplasm positive regulation of endocytosis,
water homeostasis,
excretion,
sodium ion transport,
interspecies interaction between organisms,
cellular sodium ion homeostasis,
regulation of protein catabolic process,
response to metal ion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 342 REPSSRLRSCSVTDAVAEQGH SGK_group 12911626
LTP
0.96
 - -
0.73
 - medium
S 342 REPSSRLRSCSVTDAVAEQGH SGK_group 16716084
LTP
0.96
 - -
0.73
 - medium
T 367 SAPAGRARSSTVTGGEEPTPS SGK_group 15140763
LTP
0.04
 MOD_PKA_2
 - -
0.90
 - medium
S 448 EPQIRRPRSLSSPTVTLSAPL SGK_group 12911626
LTP
1.00
 - -
0.74
 - medium
S 448 EPQIRRPRSLSSPTVTLSAPL SGK_group 16716084
LTP
1.00
 - -
0.74
 - medium
S 448 EPQIRRPRSLSSPTVTLSAPL SGK_group 15677482
LTP
1.00
 - -
0.74
 - medium

Substrate: ETS domain protein Elk-1 (Transcription factor)
Seq-ID: ENSRNOP00000013522 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding nucleus
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 159 RNEYMRSGLYSTFTIQSLQPQ SGK_group 18088355
LTP
0.90
 - -
0.52
 - medium
T 160 NEYMRSGLYSTFTIQSLQPQP SGK_group 18088355
LTP
0.15
 - -
0.54
 - medium

Substrate: Forkhead box protein O1A (Forkhead box protein O1A)
Seq-ID: Q12778 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
transcription activator activity,
protein binding		 cytosol,
nucleoplasm		 transcription,
anti-apoptosis,
negative regulation of stress-activated MAPK cascade,
positive regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 24 FEPLPRPRSCTWPLPRPEFSQ SGK_group 11410590
LTP
1.00
 MOD_PKB_1
 YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAZ 14-3-3		 -
0.70
 - medium
S 256 SGKSPRRRAASMDNNSKFAKS SGK_group 11410590
LTP
1.00
 MOD_PKB_1
 - Fork_head
0.74
 - medium
S 319 NWSTFRPRTSSNASTISGRLS SGK_group 11410590
LTP
1.00
 MOD_PKB_1
 - -
0.59
 - medium

Substrate: Forkhead box protein O3A (Forkhead box protein O3A (Forkhead in rhabdomyosarcoma-like 1))
Seq-ID: O43524 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-14323   1433Z_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
protein kinase binding,
transcription activator activity,
sequence-specific DNA binding transcription factor activity		 cytosol,
nucleus		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
transcription,
apoptosis,
positive regulation of erythrocyte differentiation,
positive regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 32 FEPQSRPRSCTWPLQRPELQA SGK_group 11154281
LTP
1.00
 MOD_PKB_1
 YWHAZ 14-3-3 -
0.89
 --
S 253 SGKAPRRRAVSMDNSNKYTKS SGK_group 11154281
LTP
1.00
 MOD_PKB_1
 YWHAZ 14-3-3 Fork_head
0.71
 2UZK 146.72%
S 315 AWTDFRSRTNSNASTVSGRLS SGK_group 11154281
LTP
1.00
 - -
0.58
 --

Substrate: GSK-3 beta (Glycogen synthase kinase-3 beta)
Seq-ID: P49841 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-65985   DBPA_HUMAN
MINT-65986   YBOX1_HUMAN
MINT-2837737   PSN1_HUMAN
MINT-3974216   TAU_HUMAN
MINT-4049759   PCM1_HUMAN
MINT-4049773   NIN_HUMAN
MINT-4508051   CTNB1_HUMAN
MINT-4508259   AXN1_HUMAN
MINT-4793253   P53_HUMAN
MINT-6761890   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
tau-protein kinase activity,
p53 binding,
beta-catenin binding,
ATP binding,
protein kinase A catalytic subunit binding,
NF-kappaB binding		 Axin-APC-beta-catenin-GSK3B complex,
beta-catenin destruction complex,
cytosol,
nucleus		 positive regulation of protein catabolic process,
hippocampus development,
negative regulation of apoptosis,
positive regulation of protein export from nucleus,
positive regulation of Rac GTPase activity,
positive regulation of protein complex assembly,
peptidyl-serine phosphorylation,
glycogen metabolic process,
superior temporal gyrus development,
canonical Wnt receptor signaling pathway,
ER overload response,
negative regulation of protein binding,
positive regulation of cell-matrix adhesion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 21 AESCKPVQQPSAFGSMKVSRD SGK_group 12054501
LTP
0.24
 - -
0.47
 --

Substrate: Huntingtin (DNA binding protein)
Seq-ID: P42858 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14843   SP1_HUMAN
MINT-15358   OPTN_HUMAN
MINT-3978197   UT14A_HUMAN
MINT-3978299   ELP1_HUMAN
MINT-3978316   KU70_HUMAN
MINT-3978554   PROF2_HUMAN
MINT-3978605   MTSS1_HUMAN
MINT-3978637   GASP2_HUMAN
MINT-3981338   GIT1_HUMAN
MINT-3981354   CHD3_HUMAN
MINT-7102030   PR40A_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription corepressor activity,
microtubule binding,
transporter activity		 Golgi apparatus,
nuclear periphery,
soluble fraction		 induction of apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 421 EESGGRSRSGSIVELIAGGGS SGK_group 14725621
LTP
1.00
 MOD_PKB_1
 - -
0.54
 - medium

Substrate: MAP3K3 (Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.1.-) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)
Seq-ID: Q99759 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-16168   M3K5_HUMAN
MINT-48367   BAG2_HUMAN
MINT-48368   AIFM1_HUMAN
MINT-48370   RPAP3_HUMAN
MINT-48371   NEMO_HUMAN
MINT-48373   HS71L_HUMAN
MINT-48374   HSP74_HUMAN
MINT-48375   TCPQ_HUMAN
MINT-48377   GRP78_HUMAN
MINT-48378   DREB_HUMAN
MINT-48379   DNJB4_HUMAN
MINT-48380   HSP7C_HUMAN
MINT-48381   TMOD3_HUMAN
MINT-48382   IKKA_HUMAN
MINT-48384   UBL4A_HUMAN
MINT-48389   ADT2_HUMAN
MINT-48390   HSP72_HUMAN
MINT-48392   GRP75_HUMAN
MINT-48393   SYMC_HUMAN
MINT-48394   COR1C_HUMAN
MINT-48395   RUVB2_HUMAN
MINT-48396   SUGT1_HUMAN
MINT-48397   IQGA1_HUMAN
MINT-48399   MYO1C_HUMAN
MINT-48402   EPIPL_HUMAN
MINT-48403   SERA_HUMAN
MINT-48406   DNJA1_HUMAN
MINT-48407   CDC37_HUMAN
MINT-48408   SYIC_HUMAN
MINT-48410   ACTN4_HUMAN
MINT-48411   HNRH1_HUMAN
MINT-48413   C1QBP_HUMAN
MINT-48414   EF1A2_HUMAN
MINT-48416   SPTA2_HUMAN
MINT-48417   PFD4_HUMAN
MINT-48420   MATR3_HUMAN
MINT-48421   1433T_HUMAN
MINT-48422   TCPA_HUMAN
MINT-48425   MYH10_HUMAN
MINT-48426   PYR1_HUMAN
MINT-48428   ACTG_HUMAN
MINT-48430   TERA_HUMAN
MINT-48433   CLH1_HUMAN
MINT-48434   IKKB_HUMAN
MINT-48435   STUB1_HUMAN
MINT-48437   GNAI2_HUMAN
MINT-48444   PP1A_HUMAN
MINT-48449   F10A1_HUMAN
MINT-48451   TBB6_HUMAN
MINT-48453   NUDC_HUMAN
MINT-48456   CALM_HUMAN
MINT-48458   TFG_HUMAN
MINT-48461   FAS_HUMAN
MINT-48462   TBB5_HUMAN
MINT-48463   K6PL_HUMAN
MINT-48464   TBB3_HUMAN
MINT-48467   TBB4_HUMAN
MINT-48468   RS27_HUMAN
MINT-48469   K1967_HUMAN
MINT-48470   MPRIP_HUMAN
MINT-48472   SCRIB_HUMAN
MINT-48474   UACA_HUMAN
MINT-48475   RAI14_HUMAN
MINT-48476   TRAF7_HUMAN
MINT-48477   ALK_HUMAN
MINT-48478   DNJA3_HUMAN
MINT-48479   M3K2_HUMAN
MINT-48480   1433Z_HUMAN
MINT-48481   FLNA_HUMAN
MINT-48483   MYPT1_HUMAN
MINT-48484   MARK2_HUMAN
MINT-48485   MYH9_HUMAN
MINT-48486   LYN_HUMAN
MINT-48488   SMRC2_HUMAN
MINT-48490   VIME_HUMAN
MINT-48491   1433B_HUMAN
MINT-48492   1433F_HUMAN
MINT-48494   H4_HUMAN
MINT-48495   SPTB2_HUMAN
MINT-48496   ADT3_HUMAN
MINT-48497   HS90A_HUMAN
MINT-48499   F10A4_HUMAN
MINT-48500   PYGM_HUMAN
MINT-48501   PP1G_HUMAN
MINT-48504   PRKDC_HUMAN
MINT-48505   MYL6_HUMAN
MINT-48506   DLG1_HUMAN
MINT-48508   G3P_HUMAN
MINT-48510   SC16A_HUMAN
MINT-48511   MP2K5_HUMAN
MINT-48513   COF2_HUMAN
MINT-48514   AKP8L_HUMAN
MINT-48516   DNJC7_HUMAN
MINT-48519   LIMA1_HUMAN
MINT-48520   HS90B_HUMAN
MINT-48521   ML12A_HUMAN
MINT-48522   GNAI3_HUMAN
MINT-48527   MYO1D_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
metal ion binding,
ATP binding,
MAP kinase kinase kinase activity,
protein binding		 positive regulation of I-kappaB kinase/NF-kappaB cascade,
MAPKKK cascade,
protein amino acid autophosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 166 QPPEPRSRHLSVSSQNPGRSS SGK_group 12761204
LTP
0.83
 - -
0.90
 - medium
S 337 QYLDPRGRLRSADSENALSVQ SGK_group 12761204
LTP
0.83
 - -
0.53
 - medium

Substrate: NDRG1 (Unclassified)
Seq-ID: Q92597 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein binding plasma membrane,
cytoplasm,
microtubule cytoskeleton,
nucleus		 response to metal ion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 328 ASMTRLMRSRTASGSSVTSLD SGK_group 15461589
LTP
0.92
 - -
0.66
 - low
S 330 MTRLMRSRTASGSSVTSLDGT SGK_group 15461589
LTP
0.94
 - -
0.66
 - low
T 346 SLDGTRSRSHTSEGTRSRSHT SGK_group 15461589
LTP
0.91
 - -
0.88
 - low
T 356 TSEGTRSRSHTSEGTRSRSHT SGK_group 15461589
LTP
0.82
 - -
0.92
 - low

Substrate: NDRG2 (Involved in neuron differentiation)
Seq-ID: Q9UN36 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cytosol,
Golgi apparatus,
perinuclear region of cytoplasm		 nervous system development,
cell differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 330 SCMTRLSRSRTASLTSAASVD SGK_group 15461589
LTP
1.00
 - -
0.49
 - low
S 332 MTRLSRSRTASLTSAASVDGN SGK_group 15461589
LTP
1.00
 - -
0.54
 - low
T 348 SVDGNRSRSRTLSQSSESGTL SGK_group 15461589
LTP
1.00
 - -
0.75
 - low

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