a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	IRF3 (Transcription factor)
Seq-ID:	Q14653 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-6540731   CBP_HUMAN MINT-6948128   TBK1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process RNA polymerase II transcription factor activity, transcription cofactor activity, sequence-specific DNA binding transcription factor activity cytosol, nucleoplasm, endosome membrane transcription from RNA polymerase II promoter, I-kappaB kinase/NF-kappaB cascade, interspecies interaction between organisms, regulation of transcription, DNA-dependent, response to virus
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	385	LVEMARVGGASSLENTVDLHI	TBK1	17526488	LTP	1.00		-	-	0.32	1QWT	40.98%
S	386	VEMARVGGASSLENTVDLHIS	TBK1	14703513	LTP	0.99		-	-	0.35	1QWT	111.48%
S	386	VEMARVGGASSLENTVDLHIS	TBK1	17526488	LTP	0.99		-	-	0.35	1QWT	111.48%

Substrate:	p65 (Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit), RelA)
Seq-ID:	Q04206 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-50016   IKBA_MOUSE MINT-50017   IKBB_MOUSE MINT-50025   KAPCA_HUMAN MINT-50073   KS6A5_HUMAN MINT-50084   KPCZ_HUMAN MINT-50090   CSK21_HUMAN MINT-50107   IKKA_HUMAN MINT-50167   IKKB_HUMAN MINT-50171   HDAC1_HUMAN MINT-50175   KAT2B_HUMAN MINT-50178   EP300_HUMAN MINT-50179   HDAC3_HUMAN MINT-58638   NCF1_HUMAN MINT-62399   TF2B_HUMAN MINT-2834593   NCOA3_HUMAN MINT-6166971   OGT1_HUMAN MINT-7235700   ASPP2_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process transcription repressor activity, transcription repressor binding, identical protein binding, protein kinase binding, ubiquitin protein ligase binding, transcription activator binding, transcription activator activity, RNA polymerase II transcription factor activity, enhancer binding, promoter binding, protein N-terminus binding, phosphate binding, NF-kappaB binding cytosol, transcription factor complex transcription, positive regulation of I-kappaB kinase/NF-kappaB cascade, cytokine-mediated signaling pathway, anti-apoptosis, defense response to virus, membrane protein intracellular domain proteolysis, cellular defense response, inflammatory response, nucleotide-binding oligomerization domain containing 2 signaling pathway, response to interleukin-1, interspecies interaction between organisms, positive regulation of NF-kappaB transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, response to UV-B, negative regulation of gene-specific transcription
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	536	GLLSGDEDFSSIADMDFSALL	TBK1	15489227	LTP	0.93		-	-	0.35	-	-