a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	CTLA-4 (CD152 antigen)
Seq-ID:	P16410 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process external side of plasma membrane, integral to plasma membrane, Golgi apparatus, perinuclear region of cytoplasm, clathrin-coated endocytic vesicle negative regulation of regulatory T cell differentiation, immune response
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	201	KKRSPLTTGVYVKMPPTEPEC	TXK	9813138	LTP	1.00		PIK3R1 SH2; PTPN11 SH2	-	0.37	-	low

Substrate:	SLP-76 (Adaptor molecule; involved in T cell AG receptor mediate signaling)
Seq-ID:	Q13094 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-15244   FYB_HUMAN MINT-16513   SHC1_HUMAN MINT-16846   CBL_HUMAN MINT-17488   FCGR1_HUMAN MINT-59471   ITK_MOUSE MINT-59473   ITK_HUMAN MINT-59474   LCK_HUMAN MINT-2837400   PLCG1_BOVIN MINT-4302560   STAM1_HUMAN MINT-4302608   STAM2_HUMAN MINT-7041321   GRAP2_HUMAN MINT-7306527   NCK1_HUMAN MINT-7306585   SRC_CHICK MINT-7306598   SRC_HUMAN MINT-7306611   FYN_HUMAN MINT-7306624   P85A_HUMAN MINT-7306637   PLCG1_HUMAN MINT-7306657   GRB2_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein binding cytosol immune response, transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	145	EEAPVEDDADYEPPPSNDEEA	TXK	8892604	LTP	1.00		ITK SH2; NCK SH2; PTPN6 SH2; VAV1 SH2	-	0.97	-	medium

Substrate:	TXK (Tyrosine kinase)
Seq-ID:	P42681 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-74794   ERBB2_HUMAN MINT-74795   ERBB3_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process non-membrane spanning protein tyrosine kinase activity, ATP binding, protein binding cytoplasm protein amino acid phosphorylation, intracellular protein kinase cascade
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	91	AEEKIQVKALYDFLPREPCNL	TXK	12081135	LTP	1.00		-	SH3	0.18	-	low