| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| CDK5 |
Cell division protein kinase 5 |
ErbB-3 class receptor binding,
tau-protein kinase activity,
acetylcholine receptor activator activity,
ErbB-2 class receptor binding,
cyclin-dependent protein kinase activity,
ATP binding,
p53 binding |
neuronal cell body,
cytosol,
growth cone,
filopodium,
dendrite,
neuromuscular junction,
lamellipodium,
axon,
membrane |
central nervous system neuron development,
serine phosphorylation of STAT3 protein,
synaptic transmission, dopaminergic,
positive regulation of protein kinase activity,
hippocampus development,
sensory perception of pain,
regulation of cell migration,
positive regulation of neuron apoptosis,
negative regulation of protein ubiquitination,
intracellular protein transport,
cell-matrix adhesion,
dendrite morphogenesis,
regulation of excitatory postsynaptic membrane potential,
synaptic transmission, glutamatergic,
cell proliferation,
embryo development,
motor axon guidance,
layer formation in the cerebral cortex,
Schwann cell development,
cell division,
corpus callosum development,
negative regulation of synaptic plasticity,
negative regulation of protein export from nucleus,
receptor clustering,
neuron migration,
visual learning,
receptor catabolic process,
neuron apoptosis,
skeletal muscle tissue development,
behavioral response to cocaine,
positive regulation of calcium ion-dependent exocytosis,
cerebellar cortex formation,
negative regulation of cell cycle |
| CDK5 activator 1 |
|
cadherin binding,
cyclin-dependent protein kinase 5 activator activity,
cyclin-dependent protein kinase activity,
calcium ion binding |
plasma membrane,
neuronal cell body,
cyclin-dependent protein kinase 5 holoenzyme complex,
perinuclear region of cytoplasm,
growth cone,
dendritic spine,
contractile fiber,
neuromuscular junction,
axon |
regulation of neuron differentiation,
regulation of cyclin-dependent protein kinase activity,
positive regulation of neuron apoptosis,
neuron cell-cell adhesion,
muscarinic acetylcholine receptor signaling pathway,
cell proliferation,
embryo development,
brain development,
protein amino acid phosphorylation,
axon guidance,
ionotropic glutamate receptor signaling pathway,
axonal fasciculation,
neuron migration,
axon extension |
| CDK5RAP2 |
microtubule binding, neuronal Cdc2-like kinase binding |
neuronal Cdc2-like kinase binding,
microtubule binding |
cytosol,
centrosome |
regulation of neuron differentiation,
brain development |
