a database of S/T/Y phosphorylation sites
Statistics
:
Instances
42.914
Kinases
299
References
3.657
Sequences
11.224
Substrates
8.698
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Name
Description
Molecular Function
Cellular Component
Biological Process
CSK
Cytoplasmic tyrosine kinase
non-membrane spanning protein tyrosine kinase activity
,
ATP binding
,
protein C-terminus binding
cytosol
protein amino acid phosphorylation
PCSK9
identical protein binding
,
serine-type endopeptidase activity
,
apolipoprotein receptor binding
,
very-low-density lipoprotein receptor binding
,
low-density lipoprotein receptor binding
perinuclear region of cytoplasm
,
late endosome
,
extrinsic to external side of plasma membrane
,
lysosome
,
extracellular space
positive regulation of receptor internalization
,
cellular response to starvation
,
positive regulation of neuron apoptosis
,
cholesterol homeostasis
,
kidney development
,
regulation of receptor activity
,
cellular response to insulin stimulus
,
cholesterol metabolic process
,
protein autoprocessing
,
negative regulation of receptor recycling
,
neuron differentiation
,
negative regulation of catalytic activity
,
proteolysis
,
liver development
,
lysosomal transport
,
negative regulation of low-density lipoprotein particle clearance
,
low-density lipoprotein receptor catabolic process