| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| BRCA2 |
Breast cancer type 2 susceptibility protein |
gamma-tubulin binding,
transcription activator activity,
protease binding |
centrosome,
nucleoplasm,
BRCA2-MAGE-D1 complex,
stored secretory granule |
cell cycle cytokinesis,
negative regulation of mammary gland epithelial cell proliferation,
regulation of transcription, DNA-dependent,
regulation of S phase of mitotic cell cycle,
response to estrogen stimulus,
centrosome duplication,
response to genistein,
nucleotide-excision repair |
| SERCA2 |
Membrane transport protein |
S100 alpha binding,
ATP binding,
calcium-transporting ATPase activity,
protein C-terminus binding |
microsome,
integral to membrane,
integral to plasma membrane,
sarcoplasmic reticulum membrane |
epidermis development,
ATP biosynthetic process,
regulation of muscle contraction,
ER-nucleus signaling pathway,
sarcoplasmic reticulum calcium ion transport,
cellular calcium ion homeostasis,
cell adhesion,
regulation of the force of heart contraction,
negative regulation of heart contraction |
| CDCA2 |
n.a. |
|
nucleus |
mitosis,
cell division |
| ABCA2 |
unclassified |
ATPase activity,
ATPase activity, coupled to transmembrane movement of substances,
ATP binding |
ATP-binding cassette (ABC) transporter complex,
lysosomal membrane,
integral to membrane,
cytoplasmic membrane-bounded vesicle,
microtubule organizing center |
lipid metabolic process,
cholesterol homeostasis,
response to drug,
transport,
cholesterol metabolic process,
regulation of intracellular cholesterol transport,
regulation of transcription from RNA polymerase II promoter,
response to steroid hormone stimulus |
| BRCA2 and CDKN1A-interacting protein |
kinase regulator activity |
kinase regulator activity,
protein binding |
nuclear cyclin-dependent protein kinase holoenzyme complex |
regulation of cyclin-dependent protein kinase activity,
DNA repair,
cell cycle |
| Ca2 |
Enzyme: Carbonic anhydrase |
carbonate dehydratase activity |
cytosol |
morphogenesis of an epithelium,
secretion,
one-carbon metabolic process,
carbon dioxide transport |
| Partner and localizer of BRCA2. |
|
|
nucleoplasm |
|
