Name | Description | Molecular Function | Cellular Component | Biological Process |
Dual specificity phosphatase 3 |
Dual specificity phosphatase |
protein tyrosine phosphatase activity, MAP kinase phosphatase activity, protein tyrosine/serine/threonine phosphatase activity |
cytosol, immunological synapse, nucleoplasm |
negative regulation of T cell activation, inactivation of MAPK activity, positive regulation of mitotic cell cycle, peptidyl-tyrosine dephosphorylation, negative regulation of JNK cascade, negative regulation of ERK1 and ERK2 cascade, negative regulation of T cell receptor signaling pathway |
ATP-citrate synthase |
ATPase |
ATP citrate synthase activity, metal ion binding, ATP binding, succinate-CoA ligase (ADP-forming) activity, citrate (pro-3S)-lyase activity, protein binding |
cytoplasm, cytosol, soluble fraction, mitochondrion, citrate lyase complex |
fatty acid biosynthetic process, citrate metabolic process, cellular carbohydrate metabolic process, coenzyme A metabolic process, ATP catabolic process, acetyl-CoA biosynthetic process, lipid biosynthetic process |
Cleavage and polyadenylation specificity factor 1 |
RNA binding protein |
mRNA 3`-UTR binding, protein binding |
mRNA cleavage and polyadenylation specificity factor complex |
mRNA polyadenylation, RNA splicing, mRNA cleavage |
Cleavage and polyadenylation specificity factor 2 |
RNA binding protein |
RNA binding, hydrolase activity, protein binding |
nucleus |
histone mRNA 3`-end processing, RNA splicing |
Dual specificity tyrosine-phosphorylation regulated kinase 3 |
Ser/Thr protein kinase family |
ATP binding, magnesium ion binding, protein serine/threonine kinase activity, protein tyrosine kinase activity, protein binding |
nucleus |
protein amino acid phosphorylation, erythrocyte differentiation |
Isocitric dehydrogenase |
Isocitrate and isopropylmalate dehydrogenases family |
isocitrate dehydrogenase (NAD+) activity, ATP binding, magnesium ion binding, NAD or NADH binding |
mitochondrion |
tricarboxylic acid cycle, oxidation reduction, isocitrate metabolic process |
Cit |
Unclassified |
metal ion binding, ATP binding, SH3 domain binding, protein serine/threonine kinase activity, small GTPase regulator activity |
cytoplasm, vacuole, actin cytoskeleton, ruffle |
dendrite development, generation of neurons, cytokinesis, spermatogenesis, mitosis, mitotic metaphase/anaphase transition, protein amino acid phosphorylation, negative regulation of dendrite morphogenesis, cell division, mitotic sister chromatid segregation |
Dual specificity protein kinase CLK4 |
unclassified |
ATP binding, protein serine/threonine kinase activity, protein tyrosine kinase activity |
nucleus |
|
Dual specificity protein kinase CLK3 |
ATP binding |
ATP binding, protein serine/threonine kinase activity, protein tyrosine kinase activity |
acrosomal vesicle, nucleus |
protein amino acid autophosphorylation, peptidyl-tyrosine phosphorylation |
cit-1.1 |
|
|
|
regulation of transcription, transcription |
CITED1 |
|
promoter binding, transcription repressor activity, LBD domain binding, protein C-terminus binding, co-SMAD binding, transcription coactivator activity, sequence-specific DNA binding transcription factor activity |
cytosol, nucleus |
branching involved in ureteric bud morphogenesis, melanocyte differentiation, response to interferon-gamma, negative regulation of osteoblast differentiation, response to interleukin-2, response to interleukin-9, SMAD protein signal transduction, metanephros development, response to interleukin-11, response to interleukin-1, response to lipopolysaccharide, cell proliferation, response to estrogen stimulus, regulation of transcription from RNA polymerase II promoter, response to cAMP, response to interleukin-4, response to parathyroid hormone stimulus, mesenchymal to epithelial transition, melanin biosynthetic process, negative regulation of Wnt receptor signaling pathway, positive regulation of transforming growth factor beta receptor signaling pathway, transforming growth factor beta receptor signaling pathway, response to insulin stimulus, response to interleukin-6 |