Name | Description | Molecular Function | Cellular Component | Biological Process |
Dystroglycan |
Adhesion molecule |
laminin-1 binding, vinculin binding, actin binding, tubulin binding, calcium ion binding, structural constituent of muscle, alpha-actinin binding |
cytoskeleton, integral to membrane, dystroglycan complex, insoluble fraction, contractile ring, membrane raft, sarcolemma, filopodium, basement membrane, integral to membrane of membrane fraction, lamellipodium, extracellular space, nucleoplasm |
morphogenesis of an epithelial sheet, branching involved in salivary gland morphogenesis, negative regulation of cell migration, epithelial tube branching involved in lung morphogenesis, negative regulation of MAPKKK cascade, microtubule anchoring, cytoskeletal anchoring at plasma membrane, negative regulation of protein kinase B signaling cascade |
Dyskerin |
RNA binding protein |
pseudouridine synthase activity, pseudouridylate synthase activity, RNA binding, telomerase activity, protein binding |
ribonucleoprotein complex, Cajal body, telomerase holoenzyme complex, nucleolus |
rRNA modification, rRNA processing, telomere maintenance via telomerase, cell proliferation, pseudouridine synthesis |
Dystrophin |
actin binding protein |
nitric-oxide synthase binding, dystroglycan binding, structural constituent of cytoskeleton, actin binding, calcium ion binding, structural constituent of muscle, zinc ion binding |
microsome, costamere, cell-substrate junction, cytoskeleton, dystrophin-associated glycoprotein complex, membrane raft, sarcolemma, cell surface, synapse, Z disc |
regulation of transcription, neurotransmitter receptor metabolic process, peptide biosynthetic process, olfactory nerve structural organization, skeletal muscle tissue development, muscle cell homeostasis |
Dysferlin |
unclassified |
phospholipid binding |
integral to membrane, cytoplasmic vesicle membrane, sarcolemma |
|
dys-1 |
|
actin binding, calcium ion binding, acetylcholine transmembrane transporter activity, zinc ion binding |
striated muscle dense body, cytoskeleton, dystrophin-associated glycoprotein complex, sarcolemma |
positive regulation of synaptic transmission, cholinergic, synaptic transmission, cholinergic, sarcomere organization, positive regulation of locomotion, forward locomotion, locomotory behavior, muscle cell homeostasis |
Dys |
|
actin binding, calcium ion binding, zinc ion binding, WW domain binding |
cytoplasm, cytoskeleton, dystrophin-associated glycoprotein complex, sarcolemma, synapse |
imaginal disc-derived wing vein morphogenesis, regulation of neurotransmitter secretion, imaginal disc-derived wing vein specification, neuromuscular synaptic transmission, establishment of cell polarity, muscle organ development, regulation of short-term neuronal synaptic plasticity, muscle cell homeostasis |
Zinc finger protein on ecdysone puffs |
|
single-stranded DNA binding, single-stranded RNA binding, zinc ion binding, protein binding |
microtubule associated complex, catalytic step 2 spliceosome, chromosome, precatalytic spliceosome, heterogeneous nuclear ribonucleoprotein complex |
nuclear mRNA splicing, via spliceosome, regulation of nuclear mRNA splicing, via spliceosome |