| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| VEGFR3 long form |
Vascular endothelial growth factor receptor |
ATP binding |
integral to plasma membrane |
protein amino acid phosphorylation |
| EGFR |
Receptor for EGF and other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, |
epidermal growth factor receptor activity,
identical protein binding,
ATP binding,
protein heterodimerization activity,
receptor signaling protein tyrosine kinase activity,
double-stranded DNA binding,
protein phosphatase binding,
actin filament binding,
MAP/ERK kinase kinase activity |
Shc-EGFR complex,
basolateral plasma membrane,
integral to membrane,
endocytic vesicle,
endosome,
extracellular space,
nucleus |
cerebral cortex cell migration,
protein insertion into membrane,
response to UV-A,
positive regulation of cell migration,
hair follicle development,
embryonic placenta development,
protein amino acid autophosphorylation,
ossification,
cell-cell adhesion,
positive regulation of MAP kinase activity,
salivary gland morphogenesis,
cell proliferation,
morphogenesis of an epithelial fold,
activation of phospholipase C activity,
positive regulation of nitric oxide biosynthetic process,
positive regulation of cyclin-dependent protein kinase activity involved in G1/S,
positive regulation of catenin protein nuclear translocation,
regulation of nitric-oxide synthase activity,
positive regulation of protein kinase B signaling cascade,
positive regulation of epithelial cell proliferation,
digestive tract morphogenesis,
activation of phospholipase A2 activity by calcium-mediated signaling,
regulation of peptidyl-tyrosine phosphorylation,
positive regulation of phosphorylation |
| VEGFR-1 |
Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. |
vascular endothelial growth factor receptor activity,
identical protein binding,
ATP binding,
growth factor binding |
cytoplasm,
integral to plasma membrane,
extracellular space |
patterning of blood vessels,
positive regulation of vascular endothelial growth factor receptor signaling pathway,
cell migration,
sprouting angiogenesis,
female pregnancy,
peptidyl-tyrosine phosphorylation,
cell differentiation |
| VEGFR-2 |
Receptor tyrosine kinase |
Hsp90 protein binding,
vascular endothelial growth factor receptor activity,
ATP binding,
receptor signaling protein tyrosine kinase activity,
growth factor binding,
integrin binding |
integral to plasma membrane |
positive regulation of mesenchymal cell proliferation,
positive regulation of endothelial cell proliferation,
hemopoiesis,
cell fate commitment,
cell maturation,
endothelial cell differentiation,
interspecies interaction between organisms,
branching morphogenesis of a tube,
positive regulation of positive chemotaxis,
protein amino acid phosphorylation,
angiogenesis,
cell migration,
regulation of cell shape,
surfactant homeostasis,
positive regulation of epithelial cell proliferation,
vasculogenesis,
positive regulation of endothelial cell migration,
lung alveolus development,
positive regulation of focal adhesion assembly,
calcium ion homeostasis,
ovarian follicle development |
