| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| NHERF-1 |
Membrane bound ligand |
PDZ domain binding,
beta-2 adrenergic receptor binding |
cytoplasm,
microvillus,
apical plasma membrane,
ruffle,
actin cytoskeleton,
filopodium,
intracellular membrane-bounded organelle,
endomembrane system |
Wnt receptor signaling pathway,
regulation of sodium:hydrogen antiporter activity,
cellular phosphate ion homeostasis,
protein complex assembly |
| Tumor necrosis factor receptor superfamily member 16 |
Cell surface receptor |
|
cytosol,
endosome,
integral to plasma membrane,
nucleoplasm |
induction of apoptosis by extracellular signals,
negative regulation of axonogenesis,
apoptosis,
positive regulation of axonogenesis,
anti-apoptosis,
membrane protein intracellular domain proteolysis,
negative regulation of cell cycle |
| Tumor necrosis factor receptor superfamily member EDAR |
Cell surface receptor |
transmembrane receptor activity,
protein binding |
integral to membrane |
epidermis development,
apoptosis,
cell differentiation |
| NHERF-2 |
Adapter molecule |
protein C-terminus binding |
cytoplasm,
apical plasma membrane,
nucleus,
endomembrane system |
protein complex assembly |
| TRERF1 |
Unclassified |
ligand-dependent nuclear receptor transcription coactivator activity,
DNA bending activity,
RNA polymerase II transcription mediator activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity |
nucleus |
positive regulation of transcription, DNA-dependent,
regulation of hormone biosynthetic process,
homeostatic process,
transcription,
steroid biosynthetic process,
cholesterol catabolic process,
multicellular organismal development |
| ERF |
ligand-regulated transcription factor activity, transcription corepressor activity |
transcription corepressor activity,
ligand-regulated transcription factor activity,
sequence-specific DNA binding,
sequence-specific DNA binding transcription factor activity |
nucleus |
cell proliferation,
transcription,
regulation of transcription from RNA polymerase II promoter |
| Interferon regulatory factor 2 binding protein 1 variant |
unclassified |
|
nucleus |
regulation of transcription,
transcription |
| Interferon-induced protein with tetratricopeptide repeats 2 |
binding |
binding |
|
|
| Protein activator of the interferon-induced protein kinase |
enzyme activator activity |
double-stranded RNA binding,
enzyme activator activity,
protein homodimerization activity,
protein binding |
perinuclear region of cytoplasm |
skeletal system morphogenesis,
negative regulation of cell proliferation,
production of siRNA involved in RNA interference,
outer ear morphogenesis,
middle ear morphogenesis,
induction of apoptosis,
protein amino acid phosphorylation,
response to stress,
immune response,
response to virus |
