| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| Ena |
Abl substrate with SH3 binding properties |
actin binding,
SH3 domain binding |
cytosol,
cytoskeleton,
lamellipodium,
adherens junction,
filopodium tip |
positive regulation of filopodium assembly,
actin filament organization,
suture of dorsal opening,
regulation of actin polymerization or depolymerization,
dendrite morphogenesis,
germ-band shortening,
axon guidance,
compound eye development,
head involution,
border follicle cell migration,
regulation of cell shape,
cytoplasmic transport, nurse cell to oocyte |
| Structural maintenance of chromosome 1-like 1 protein |
Structural maintenance of chromosome 1-like 1 protein |
chromatin binding,
ATP binding,
protein heterodimerization activity,
microtubule motor activity |
condensed chromosome kinetochore,
cytoplasm,
condensed nuclear chromosome,
cohesin core heterodimer |
meiosis,
DNA damage response, signal transduction,
cell division,
DNA repair,
negative regulation of DNA endoreduplication,
mitotic spindle organization,
mitotic sister chromatid cohesion,
response to radiation,
RNA splicing,
cell cycle checkpoint |
| L-lactate dehydrogenase A chain |
L-lactate dehydrogenase M chain (EC 1.1.1.27) (LDH-A) (from PhosphoBase) |
binding,
L-lactate dehydrogenase activity,
protein binding |
cytoplasm,
cytosol |
oxidation reduction,
glycolysis |
| Arachidonate 5 lipoxygenase |
Enzyme: Lipase |
arachidonate 5-lipoxygenase activity,
iron ion binding,
lipoxygenase activity,
protein binding |
cytosol,
nuclear envelope lumen,
nuclear membrane,
nuclear matrix |
oxidation reduction,
leukotriene biosynthetic process |
| Pyruvate dehydrogenase kinase isoform 1 |
Enzyme: Phosphotransferase |
ATP binding,
pyruvate dehydrogenase (acetyl-transferring) kinase activity,
two-component sensor activity |
mitochondrial matrix |
glucose metabolic process,
peptidyl-histidine phosphorylation,
regulation of acetyl-CoA biosynthetic process from pyruvate,
small GTPase mediated signal transduction |
| Structural maintenance of chromosome 3 |
Unclassified |
dynein binding,
ATP binding,
protein heterodimerization activity,
microtubule motor activity |
cytoplasm,
cohesin complex,
chromosome, centromeric region,
basement membrane,
lateral element,
chromatin,
spindle pole,
nuclear matrix |
mitosis,
meiosis,
cell division,
DNA repair,
negative regulation of DNA endoreduplication,
signal transduction,
mitotic spindle organization,
sister chromatid cohesion,
DNA mediated transformation |
| Cysteine dioxygenase type 1 |
Enzyme: Oxidoreductase |
cysteine dioxygenase activity |
cytosol |
taurine biosynthetic process,
oxidation reduction,
sulfur amino acid biosynthetic process,
inflammatory response |
| Structural maintenance of chromosome 4-like 1 protein |
Unclassified |
ATP binding,
protein heterodimerization activity |
cytoplasm,
condensin complex,
nucleus |
cell division,
mitotic chromosome condensation |
| Enamelin precursor |
Structural protein |
|
proteinaceous extracellular matrix |
biomineral tissue development |
| Glucose-6-phosphate 1-dehydrogenase |
Produces pentose sugars for nucleic acid synthesis |
glucose binding,
NADP or NADPH binding,
protein homodimerization activity,
glucose-6-phosphate dehydrogenase activity |
cytosol,
centrosome,
internal side of plasma membrane,
intracellular membrane-bounded organelle |
oxidation reduction,
glutathione metabolic process,
negative regulation of protein amino acid glutathionylation,
erythrocyte maturation,
cytokine production,
ribose phosphate biosynthetic process,
cholesterol biosynthetic process,
pentose-phosphate shunt, oxidative branch,
cellular response to oxidative stress,
glucose 6-phosphate metabolic process |
| Glucose-6-phosphate 1-dehydrogenase 2 |
Glucose-6-phosphate dehydrogenase family |
binding,
glucose-6-phosphate dehydrogenase activity |
|
oxidation reduction,
glucose metabolic process |
| Glucose-6-phosphate 1-dehydrogenase X |
Glucose-6-phosphate 1-dehydrogenase activity |
protein homodimerization activity,
glucose-6-phosphate dehydrogenase activity |
|
oxidation reduction,
pentose biosynthetic process,
response to oxidative stress,
regulation of multicellular organism growth,
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure,
erythrocyte development,
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure,
glutathione metabolic process,
glucose metabolic process,
interleukin-10 production,
interleukin-12 production,
NADP biosynthetic process |
| Glyceraldehyde-3-phosphate dehydrogenase |
Enzyme: Phosphatase |
NAD or NADH binding,
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity,
protein binding |
cytoplasm,
perinuclear region of cytoplasm,
membrane |
oxidation reduction,
glycolysis |
| Isocitric dehydrogenase |
Isocitrate and isopropylmalate dehydrogenases family |
isocitrate dehydrogenase (NAD+) activity,
ATP binding,
magnesium ion binding,
NAD or NADH binding |
mitochondrion |
tricarboxylic acid cycle,
oxidation reduction,
isocitrate metabolic process |
| L-lactate dehydrogenase B chain |
LDH/MDH superfamily |
L-lactate dehydrogenase activity |
|
oxidation reduction,
glycolysis |
| Malate dehydrogenase, mitochondrial precursor |
LDH/MDH superfamily. MDH type 1 family |
L-malate dehydrogenase activity |
mitochondrial matrix |
tricarboxylic acid cycle,
oxidation reduction,
glycolysis,
malate metabolic process |
| Enah |
Unclassified |
actin binding,
profilin binding,
SH3 domain binding,
WW domain binding |
stress fiber,
cytosol,
cytoskeleton,
filopodium,
focal adhesion,
lamellipodium,
synapse |
neural tube closure,
actin polymerization or depolymerization,
axon guidance,
intracellular transport |
| Heme oxygenase 1 |
signal transducer activity |
enzyme binding,
signal transducer activity,
heme oxygenase (decyclizing) activity,
protein homodimerization activity,
heme binding |
microsome,
endoplasmic reticulum,
extracellular space |
heme oxidation,
oxidation reduction,
response to hydrogen peroxide,
heme catabolic process,
positive regulation of chemokine biosynthetic process,
positive regulation of smooth muscle cell proliferation,
low-density lipoprotein particle clearance,
protein homooligomerization,
cell death,
positive regulation of vasodilation,
regulation of angiogenesis,
angiogenesis,
positive regulation of I-kappaB kinase/NF-kappaB cascade,
erythrocyte homeostasis,
regulation of transcription from RNA polymerase II promoter in response to oxidative stress,
anti-apoptosis,
endothelial cell proliferation,
excretion,
negative regulation of smooth muscle cell proliferation,
negative regulation of leukocyte migration,
wound healing involved in inflammatory response,
smooth muscle hyperplasia,
response to nicotine,
iron ion homeostasis,
intracellular protein kinase cascade |
| Tenascin-R precursor |
unclassified |
sphingolipid binding,
receptor binding |
membrane raft,
proteinaceous extracellular matrix,
cell surface |
axon guidance,
signal transduction,
extracellular matrix organization,
cell adhesion |
| Tenascin |
Extracellular matrix protein |
receptor binding |
basement membrane |
mesenchymal-epithelial cell signaling involved in prostate gland development,
positive regulation of cell proliferation,
neuromuscular junction development,
prostate gland epithelium morphogenesis,
signal transduction,
cell adhesion,
positive regulation of gene expression |
| L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
|
magnesium ion binding,
holo-[acyl-carrier-protein] synthase activity,
protein binding |
cytosol |
macromolecule biosynthetic process |
| Structural maintenance of chromosomes protein 6 |
|
|
|
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