Name | Description | Molecular Function | Cellular Component | Biological Process |
HMG-I(Y) |
high mobility group protein HMG-Y (from PhosphoBase) |
peroxisome proliferator activated receptor binding, DNA binding, ligand-dependent nuclear receptor transcription coactivator activity, enzyme binding, retinoid X receptor binding, AT DNA binding, sequence-specific DNA binding transcription factor activity |
cytosol, transcription factor complex, chromatin, nucleus |
DNA unwinding involved in replication, initiation of viral infection, interspecies interaction between organisms, regulation of transcription, DNA-dependent, loss of chromatin silencing, provirus integration, protein complex assembly, transcription, nucleosome disassembly |
HMG-CoA reductase |
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (from PhosphoBase) |
hydroxymethylglutaryl-CoA reductase (NADPH) activity, NADP or NADPH binding, protein homodimerization activity, hydroxymethylglutaryl-CoA reductase activity |
microsome, integral to membrane, endoplasmic reticulum membrane |
oxidation reduction, aging, response to nutrient, farnesyl diphosphate biosynthetic process, mevalonate pathway, coenzyme A metabolic process, positive regulation of skeletal muscle tissue development, cholesterol biosynthetic process |
HMG-1L2 |
Growth factor |
DNA binding, growth factor activity, nucleotide binding, heparin binding |
cytoplasm, extracellular space, nucleus |
regulation of transcription, cell proliferation, transcription, signal transduction |
HMG-CoA synthase |
hydroxymethylglutaryl-CoA synthase activity |
hydroxymethylglutaryl-CoA synthase activity |
cytosol, soluble fraction |
isoprenoid biosynthetic process, cholesterol biosynthetic process |
hmg-1.1 |
|
DNA binding |
nucleus |
|
hmg-11 |
|
|
|
|
hmg-12 |
|
DNA binding |
|
embryo development ending in birth or egg hatching |
hmg-3 |
|
DNA binding |
chromosome, nucleus |
locomotion, cytokinesis, embryo development ending in birth or egg hatching, regulation of transcription, nematode larval development, positive regulation of growth rate, DNA replication, transcription, DNA repair, body morphogenesis, reproduction, axonal fasciculation, growth, positive regulation of multicellular organism growth |
hmg-4 |
|
DNA binding |
chromosome, nucleus |
locomotion, embryo development ending in birth or egg hatching, regulation of transcription, nematode larval development, positive regulation of growth rate, DNA replication, hermaphrodite genitalia development, transcription, DNA repair, growth |