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NameDescriptionMolecular FunctionCellular ComponentBiological Process
IL-6R (gp130) gp130 is shared by members of the IL-6 family ciliary neurotrophic factor receptor activity,
ciliary neurotrophic factor receptor binding,
protein homodimerization activity,
interleukin-27 receptor activity
extracellular region,
external side of plasma membrane,
oncostatin-M receptor complex,
ciliary neurotrophic factor receptor complex,
interleukin-6 receptor complex,
extracellular space
regulation of Notch signaling pathway,
positive regulation vascular endothelial growth factor production,
positive regulation of anti-apoptosis,
response to cytokine stimulus,
glycogen metabolic process,
positive regulation of tyrosine phosphorylation of Stat1 protein,
positive regulation of adaptive immune response,
positive regulation of osteoblast differentiation,
positive regulation of tyrosine phosphorylation of Stat3 protein,
leukemia inhibitory factor signaling pathway,
negative regulation of interleukin-6-mediated signaling pathway,
ciliary neurotrophic factor-mediated signaling pathway,
positive regulation of T cell proliferation,
interleukin-27-mediated signaling pathway,
positive regulation of astrocyte differentiation,
positive regulation of acute inflammatory response,
positive regulation of cardiac muscle hypertrophy

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