Name | Description | Molecular Function | Cellular Component | Biological Process |
MAP3K9 |
ATP binding, JUN kinase kinase kinase activity |
JUN kinase kinase kinase activity, MAP kinase kinase activity, ATP binding, protein homodimerization activity |
|
activation of JUN kinase activity, protein amino acid autophosphorylation |
CDK9 |
cyclin-dependent protein kinase activity, protein binding |
DNA binding, cyclin-dependent protein kinase activity, ATP binding, RNA polymerase II carboxy-terminal domain kinase activity, protein binding |
transcription elongation factor complex |
regulation of transcription, cell proliferation, protein amino acid phosphorylation, transcription initiation from RNA polymerase II promoter, RNA elongation from RNA polymerase II promoter |
NEK9 |
ser/thr kinase |
metal ion binding, ATP binding, protein serine/threonine kinase activity, protein kinase binding |
mitochondrion, nucleus |
mitosis, protein amino acid phosphorylation, cell division |
DOCK9 |
guanine nucleotide exchange factor |
guanyl-nucleotide exchange factor activity, GTP binding, GTPase binding |
membrane, endomembrane system |
|
ZK909.6 |
|
|
|
|
ZK973.2 |
|
chromatin binding |
chromatin, nucleus |
chromatin assembly or disassembly |
hem, MKK9 |
|
ATP binding, MAP-kinase scaffold activity, JUN kinase kinase activity, protein kinase binding, receptor signaling protein serine/threonine kinase activity, protein tyrosine kinase activity |
axon |
regulation of hemocyte differentiation, JNK cascade, positive regulation of JUN kinase activity, imaginal disc eversion, establishment of planar polarity, micropyle formation, carbohydrate homeostasis, actin filament bundle assembly, wound healing, lamellipodium assembly, protein amino acid phosphorylation, chorion-containing eggshell pattern formation, determination of adult lifespan, dorsal closure, spreading of leading edge cells, response to heat, border follicle cell migration, imaginal disc fusion, thorax closure, triglyceride homeostasis, dorsal appendage formation, axon extension, filopodium assembly, basement membrane disassembly |
K9 |
|
structural constituent of cytoskeleton, protein binding |
|
intermediate filament organization, skin development |
PCSK9 |
|
identical protein binding, serine-type endopeptidase activity, apolipoprotein receptor binding, very-low-density lipoprotein receptor binding, low-density lipoprotein receptor binding |
perinuclear region of cytoplasm, late endosome, extrinsic to external side of plasma membrane, lysosome, extracellular space |
positive regulation of receptor internalization, cellular response to starvation, positive regulation of neuron apoptosis, cholesterol homeostasis, kidney development, regulation of receptor activity, cellular response to insulin stimulus, cholesterol metabolic process, protein autoprocessing, negative regulation of receptor recycling, neuron differentiation, negative regulation of catalytic activity, proteolysis, liver development, lysosomal transport, negative regulation of low-density lipoprotein particle clearance, low-density lipoprotein receptor catabolic process |