| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| LckBP1 |
Hematopoietic cell-specific LYN substrate 1 |
protein complex binding,
SH3 domain binding,
sequence-specific DNA binding transcription factor activity |
mitochondrion,
nucleus,
membrane |
intracellular signaling pathway,
response to hormone stimulus,
positive regulation of tyrosine phosphorylation of STAT protein,
regulation of transcription, DNA-dependent,
positive regulation of cell proliferation,
erythrocyte differentiation |
| LCK |
proto-oncogene tyrosine-protein kinase Lck (from PhosphoBase) |
protein serine/threonine phosphatase activity,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
CD4 receptor binding,
phosphoinositide 3-kinase binding,
protein C-terminus binding,
protein kinase binding,
glycoprotein binding,
CD8 receptor binding,
SH2 domain binding,
ATPase binding |
plasma membrane,
cytosol,
Golgi apparatus,
membrane raft,
pericentriolar material |
T cell differentiation,
response to drug,
activation of caspase activity,
positive regulation of T cell activation,
release of sequestered calcium ion into cytosol,
interspecies interaction between organisms,
induction of apoptosis,
protein amino acid phosphorylation,
positive regulation of T cell receptor signaling pathway,
cellular zinc ion homeostasis |
| MLCK |
Serine/threonine Kinase |
myosin light chain kinase activity,
metal ion binding,
actin-dependent ATPase activity,
ATP binding,
calmodulin binding,
actin binding |
cytoplasm,
cytosol,
membrane |
cytokinesis,
protein amino acid autophosphorylation,
cAMP-mediated signaling,
protein amino acid phosphorylation,
muscle contraction,
regulation of chemotaxis,
cGMP-mediated signaling |
