Name | Description | Molecular Function | Cellular Component | Biological Process |
MAP3K7 |
Mitogen-activated protein kinase kinase kinase 7 |
MAP kinase kinase activity, ATP binding, magnesium ion binding, protein serine/threonine kinase activity, MAP kinase kinase kinase activity, protein binding |
cytosol, endosome membrane |
MAPKKK cascade, positive regulation of JUN kinase activity, activation of NF-kappaB-inducing kinase activity, I-kappaB phosphorylation, positive regulation of T cell activation, T cell receptor signaling pathway, positive regulation of JNK cascade, negative regulation of apoptosis, angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of T cell cytokine production, transforming growth factor beta receptor signaling pathway, neural tube formation, positive regulation of interleukin-2 production |
Map3k7ip2 |
Ser/Thr kinase |
K63-linked polyubiquitin binding, zinc ion binding |
plasma membrane, cytosol, nucleus, endosome membrane |
positive regulation of protein kinase activity, positive regulation of I-kappaB kinase/NF-kappaB cascade |