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NameDescriptionMolecular FunctionCellular ComponentBiological Process
P130Cas Adaptor molecule. Contain 15 YxxP motifs. signal transducer activity,
SH3 domain binding,
protein kinase binding,
protein phosphatase binding
cytoplasm,
cytosol,
ruffle,
focal adhesion,
membrane fraction,
lamellipodium
regulation of cell growth,
positive regulation of cell migration,
epidermal growth factor receptor signaling pathway,
actin filament organization,
regulation of apoptosis,
platelet-derived growth factor receptor signaling pathway,
T cell receptor signaling pathway,
cell proliferation,
B cell receptor signaling pathway,
cell division,
nerve growth factor receptor signaling pathway,
cell migration,
integrin-mediated signaling pathway,
cell adhesion,
insulin receptor signaling pathway,
G-protein coupled receptor protein signaling pathway
p130Cas-associated protein P140Cap family protein kinase binding cell junction,
cytoplasm,
actin cytoskeleton,
dendrite,
axon,
postsynaptic membrane,
postsynaptic density
regulation of cell migration,
exocytosis,
negative regulation of protein tyrosine kinase activity,
substrate adhesion-dependent cell spreading,
positive regulation of protein tyrosine kinase activity,
regulation of dendritic spine morphogenesis,
negative regulation of cell adhesion

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