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NameDescriptionMolecular FunctionCellular ComponentBiological Process
Probable transcription factor PML metal ion binding zinc ion binding,
protein binding
intracellular
PML protein binding DNA binding,
transcription repressor activity,
cobalt ion binding,
protein heterodimerization activity,
protein homodimerization activity,
ubiquitin protein ligase binding,
SMAD binding,
transcription coactivator activity,
zinc ion binding,
protein binding
cytoplasm,
insoluble fraction,
PML body,
nuclear membrane,
nucleolus,
nuclear matrix,
nucleus
protein stabilization,
SMAD protein nuclear translocation,
negative regulation of angiogenesis,
negative regulation of cell proliferation,
branching involved in mammary gland duct morphogenesis,
cell cycle arrest,
activation of caspase activity,
cell fate commitment,
negative regulation of transcription,
response to cytokine stimulus,
DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis,
myeloid cell differentiation,
interspecies interaction between organisms,
protein targeting,
maintenance of protein location in nucleus,
induction of apoptosis,
DNA damage response, signal transduction resulting in induction of apoptosis,
negative regulation of translation in response to oxidative stress,
common-partner SMAD protein phosphorylation,
positive regulation of defense response to virus by host,
response to UV,
protein complex assembly,
retinoic acid receptor signaling pathway,
transcription,
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest,
response to hypoxia,
negative regulation of cell growth,
regulation of MHC class I biosynthetic process,
cell aging,
positive regulation of histone deacetylation,
response to gamma radiation,
PML body organization,
transforming growth factor beta receptor signaling pathway,
negative regulation of mitotic cell cycle

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