a database of S/T/Y phosphorylation sites
Statistics
:
Instances
42.914
Kinases
299
References
3.657
Sequences
11.224
Substrates
8.698
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No perfect match found, you are looking at a relaxed search.
Name
Description
Molecular Function
Cellular Component
Biological Process
PPARG
Transcription factor
specific transcriptional repressor activity
,
chromatin binding
,
promoter binding
,
drug binding
,
retinoid X receptor binding
,
steroid hormone receptor activity
,
transcription activator binding
,
transcription activator activity
,
arachidonic acid binding
,
zinc ion binding
,
sequence-specific DNA binding transcription factor activity
,
prostaglandin receptor activity
cytosol
,
transcriptional repressor complex
,
nucleus
negative regulation of gene-specific transcription from RNA polymerase II promoter
,
positive regulation of gene-specific transcription from RNA polymerase II promoter
,
regulation of blood pressure
,
epithelial cell differentiation
,
negative regulation of cell proliferation
,
white fat cell differentiation
,
lipoprotein transport
,
negative regulation of receptor biosynthetic process
,
cellular response to organic cyclic substance
,
placenta development
,
activation of caspase activity
,
cell fate commitment
,
inflammatory response
,
cell maturation
,
brown fat cell differentiation
,
negative regulation of macrophage derived foam cell differentiation
,
low-density lipoprotein receptor biosynthetic process
,
monocyte differentiation
,
regulation of cholesterol transporter activity
,
positive regulation of fat cell differentiation
,
response to low-density lipoprotein stimulus
,
cellular response to lithium ion
,
cellular response to insulin stimulus
,
negative regulation of cholesterol storage
,
induction of apoptosis
,
negative regulation of cytokine production
,
transcription
,
glucose homeostasis
,
negative regulation of sequestering of triglyceride
,
positive regulation of transcription factor activity
,
innate immune response
,
lipid homeostasis
,
response to lipid
,
long-chain fatty acid transport
PPAR
Nuclear receptor
lipid binding
,
drug binding
,
steroid hormone receptor activity
,
sequence-specific DNA binding
,
transcription activator activity
,
zinc ion binding
,
sequence-specific DNA binding transcription factor activity
nucleus
negative regulation of gene-specific transcription from RNA polymerase II promoter
,
negative regulation of receptor biosynthetic process
,
positive regulation of fatty acid beta-oxidation
,
fatty acid metabolic process
,
negative regulation of macrophage derived foam cell differentiation
,
negative regulation of appetite
,
negative regulation of cholesterol storage
,
transcription from RNA polymerase II promoter
,
negative regulation of sequestering of triglyceride
,
fatty acid transport
PPARGC-1 alpha
Transcription regulatory protein
DNA binding
,
ligand-dependent nuclear receptor transcription coactivator activity
,
androgen receptor binding
,
RNA binding
,
RNA polymerase II transcription mediator activity
,
nucleotide binding
,
ligand-dependent nuclear receptor binding
DNA-directed RNA polymerase II, core complex
protein stabilization
,
gluconeogenesis
,
positive regulation of gene-specific transcription
,
brown fat cell differentiation
,
temperature homeostasis
,
fatty acid oxidation
,
mitochondrion organization
,
digestion
,
mRNA processing
,
positive regulation of gluconeogenesis
,
positive regulation of transcription factor activity
,
cellular glucose homeostasis
,
positive regulation of histone acetylation
,
androgen receptor signaling pathway
,
transcription initiation from RNA polymerase II promoter
,
RNA splicing
,
positive regulation of fatty acid oxidation
,
response to starvation
Nuclear mitotic apparatus protein 1
Structural protein
structural molecule activity
,
protein binding
spindle microtubule
,
cytosol
,
chromosome
,
spindle pole
,
nucleoplasm
nucleus organization
,
mitotic anaphase
PPARGC1B
ligand-dependent nuclear receptor transcription coactivator activity
,
RNA binding
,
RNA polymerase II transcription mediator activity
,
nucleotide binding
,
estrogen receptor binding
,
AF-2 domain binding
,
receptor activator activity
mediator complex
transcription
,
estrogen receptor signaling pathway
,
positive regulation of transcription from RNA polymerase II promoter