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NameDescriptionMolecular FunctionCellular ComponentBiological Process
PPARG Transcription factor specific transcriptional repressor activity,
chromatin binding,
promoter binding,
drug binding,
retinoid X receptor binding,
steroid hormone receptor activity,
transcription activator binding,
transcription activator activity,
arachidonic acid binding,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
prostaglandin receptor activity
cytosol,
transcriptional repressor complex,
nucleus
negative regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
regulation of blood pressure,
epithelial cell differentiation,
negative regulation of cell proliferation,
white fat cell differentiation,
lipoprotein transport,
negative regulation of receptor biosynthetic process,
cellular response to organic cyclic substance,
placenta development,
activation of caspase activity,
cell fate commitment,
inflammatory response,
cell maturation,
brown fat cell differentiation,
negative regulation of macrophage derived foam cell differentiation,
low-density lipoprotein receptor biosynthetic process,
monocyte differentiation,
regulation of cholesterol transporter activity,
positive regulation of fat cell differentiation,
response to low-density lipoprotein stimulus,
cellular response to lithium ion,
cellular response to insulin stimulus,
negative regulation of cholesterol storage,
induction of apoptosis,
negative regulation of cytokine production,
transcription,
glucose homeostasis,
negative regulation of sequestering of triglyceride,
positive regulation of transcription factor activity,
innate immune response,
lipid homeostasis,
response to lipid,
long-chain fatty acid transport
PPAR Nuclear receptor lipid binding,
drug binding,
steroid hormone receptor activity,
sequence-specific DNA binding,
transcription activator activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity
nucleus negative regulation of gene-specific transcription from RNA polymerase II promoter,
negative regulation of receptor biosynthetic process,
positive regulation of fatty acid beta-oxidation,
fatty acid metabolic process,
negative regulation of macrophage derived foam cell differentiation,
negative regulation of appetite,
negative regulation of cholesterol storage,
transcription from RNA polymerase II promoter,
negative regulation of sequestering of triglyceride,
fatty acid transport
PPARGC-1 alpha Transcription regulatory protein DNA binding,
ligand-dependent nuclear receptor transcription coactivator activity,
androgen receptor binding,
RNA binding,
RNA polymerase II transcription mediator activity,
nucleotide binding,
ligand-dependent nuclear receptor binding
DNA-directed RNA polymerase II, core complex protein stabilization,
gluconeogenesis,
positive regulation of gene-specific transcription,
brown fat cell differentiation,
temperature homeostasis,
fatty acid oxidation,
mitochondrion organization,
digestion,
mRNA processing,
positive regulation of gluconeogenesis,
positive regulation of transcription factor activity,
cellular glucose homeostasis,
positive regulation of histone acetylation,
androgen receptor signaling pathway,
transcription initiation from RNA polymerase II promoter,
RNA splicing,
positive regulation of fatty acid oxidation,
response to starvation
Nuclear mitotic apparatus protein 1 Structural protein structural molecule activity,
protein binding
spindle microtubule,
cytosol,
chromosome,
spindle pole,
nucleoplasm
nucleus organization,
mitotic anaphase
PPARGC1B ligand-dependent nuclear receptor transcription coactivator activity,
RNA binding,
RNA polymerase II transcription mediator activity,
nucleotide binding,
estrogen receptor binding,
AF-2 domain binding,
receptor activator activity
mediator complex transcription,
estrogen receptor signaling pathway,
positive regulation of transcription from RNA polymerase II promoter

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