| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| Pleckstrin |
pleckstrin (platelet p47 protein) (from PhosphoBase) |
phosphatidylinositol-3,4-bisphosphate binding,
protein kinase C binding,
protein homodimerization activity |
extracellular region,
cytosol,
soluble fraction,
membrane fraction,
ruffle membrane |
cortical actin cytoskeleton organization,
positive regulation of actin filament depolymerization,
protein kinase C signaling cascade,
protein secretion by platelet,
platelet aggregation,
regulation of cell diameter,
negative regulation of calcium-mediated signaling,
vesicle docking involved in exocytosis,
negative regulation of inositol phosphate biosynthetic process,
actin cytoskeleton reorganization,
positive regulation of actin filament bundle assembly,
integrin-mediated signaling pathway,
inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway,
hemopoietic progenitor cell differentiation,
positive regulation of platelet activation,
phosphoinositide metabolic process,
positive regulation of inositol-polyphosphate 5-phosphatase activity,
positive regulation of integrin activation,
ruffle organization,
thrombin receptor signaling pathway |
| Pleckstrin homology domain containing family G member 1 |
guanyl-nucleotide exchange factor activity |
Rho guanyl-nucleotide exchange factor activity |
intracellular |
regulation of Rho protein signal transduction |
| Pleckstrin homology domain containing, family G, member 3 |
unclassified |
Rho guanyl-nucleotide exchange factor activity |
intracellular |
regulation of Rho protein signal transduction |
