| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| RET |
Probable receptor with tyrosine-protein kinase activity; important for development. |
ATP binding,
calcium ion binding,
transmembrane receptor protein tyrosine kinase activity,
protein binding |
integral to membrane |
enteric nervous system development,
posterior midgut development,
MAPKKK cascade,
neuron maturation,
transmembrane receptor protein tyrosine kinase signaling pathway,
embryonic epithelial tube formation,
protein amino acid phosphorylation,
ureteric bud development,
neural crest cell migration,
homophilic cell adhesion |
| Retinoic acid receptor RXR-alpha |
Retinoic acid receptor RXR-alpha |
retinoid-X receptor activity,
ligand-regulated transcription factor activity,
steroid hormone receptor activity,
protein heterodimerization activity,
transcription coactivator activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
vitamin D receptor binding |
nucleus |
negative regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
vitamin metabolic process,
ventricular cardiac muscle cell differentiation,
interspecies interaction between organisms,
ventricular cardiac muscle tissue morphogenesis,
regulation of branching involved in prostate gland morphogenesis,
cholesterol metabolic process,
transcription,
cardiac muscle cell proliferation,
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development,
response to retinoic acid |
| Retinoblastoma-associated protein HEC |
Cell cycle control protein |
protein binding |
Ndc80 complex,
outer kinetochore of condensed nuclear chromosome |
attachment of spindle microtubules to kinetochore,
cell division,
mitotic sister chromatid segregation,
phosphoinositide-mediated signaling,
mitotic spindle organization,
establishment of mitotic spindle orientation |
| Secretory carrier-associated membrane protein 3 |
Membrane transport protein |
|
integral to membrane,
Golgi membrane |
intracellular protein transport,
protein transport,
post-Golgi vesicle-mediated transport,
response to retinoic acid |
| Secretory carrier-associated membrane protein 1 |
Membrane transport protein |
protein binding |
integral to membrane,
recycling endosome membrane,
trans-Golgi network |
protein transport,
post-Golgi vesicle-mediated transport |
| Retinoblastoma like 1 |
Cell cycle control protein |
transcription factor binding |
|
interspecies interaction between organisms,
chromatin modification,
transcription,
cell cycle,
regulation of lipid kinase activity |
| Retinoblastoma like 2 |
Cell cycle control protein |
DNA binding,
protein binding |
transcription factor complex |
regulation of transcription,
chromatin modification,
transcription,
cell cycle,
regulation of lipid kinase activity |
| Retinoblastoma binding protein 6 |
Ubiquitin proteasome system protein |
nucleic acid binding,
ubiquitin-protein ligase activity,
zinc ion binding,
protein binding |
ubiquitin ligase complex,
chromosome,
nucleolus |
|
| Fragile X mental retardation syndrome-related protein 1 |
RNA-binding protein |
mRNA 3`-UTR binding,
G-quadruplex RNA binding,
protein binding |
costamere,
polysome,
nucleolus,
nucleus |
apoptosis,
negative regulation of translation,
muscle organ development,
cell differentiation |
| Reticulon-1 |
Possible role in neuroendocrine secretion or in ,15, trafficking in neuroendocrine cells |
signal transducer activity |
integral to membrane,
endoplasmic reticulum membrane,
integral to endoplasmic reticulum membrane |
neuron differentiation |
| Retinoic acid induced protein 3 |
Unclassified |
G-protein coupled receptor activity |
plasma membrane,
integral to membrane,
cytoplasmic vesicle membrane,
integral to plasma membrane |
|
| Retinoic acid receptor alpha |
Nuclear hormone receptor family |
retinoic acid receptor activity,
chromatin DNA binding,
transcription corepressor activity,
enzyme binding,
receptor binding,
promoter binding,
steroid hormone receptor activity,
transcription repressor activity,
protein heterodimerization activity,
retinoic acid binding,
protein domain specific binding,
retinoic acid-responsive element binding,
transcription coactivator activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
protein binding |
neuronal cell body,
cytoplasm,
dendrite,
cell surface,
nucleus |
negative regulation of cartilage development,
negative regulation of tumor necrosis factor production,
positive regulation of gene-specific transcription,
positive regulation of interleukin-5 production,
regulation of granulocyte differentiation,
spermatogenesis,
chondroblast differentiation,
ventricular cardiac muscle cell differentiation,
negative regulation of gene-specific transcription,
positive regulation of interleukin-4 production,
positive regulation of cell proliferation,
protein amino acid phosphorylation,
transcription,
ureteric bud development,
positive regulation of T-helper 2 cell differentiation,
negative regulation of granulocyte differentiation,
positive regulation of cell cycle,
response to estradiol stimulus,
negative regulation of cell differentiation,
positive regulation of binding,
cellular response to estrogen stimulus,
estrogen receptor signaling pathway,
cellular response to lipopolysaccharide,
response to retinoic acid,
cellular response to retinoic acid,
negative regulation of interferon-gamma production,
positive regulation of transcription from RNA polymerase II promoter,
apoptotic cell clearance,
negative regulation of transcription from RNA polymerase II promoter,
positive regulation of interleukin-13 production,
negative regulation of translational initiation |
| Transitional endoplasmic reticulum ATPase |
Structural protein |
ATPase activity,
lipid binding,
ATP binding,
protein domain specific binding,
protein phosphatase binding,
polyubiquitin binding |
microsome,
cytosol,
endoplasmic reticulum,
proteasome complex,
nucleus |
aggresome assembly,
activation of caspase activity,
ER-associated protein catabolic process,
positive regulation of proteasomal ubiquitin-dependent protein catabolic process,
double-strand break repair,
endoplasmic reticulum unfolded protein response,
protein ubiquitination,
retrograde protein transport, ER to cytosol |
| Retinoblastoma-associated protein RAP140 |
Unclassified |
|
|
|
| Secretogranin I |
hormone activity |
hormone activity |
extracellular region |
|
| Retinoblastoma-associated factor 600 |
binding |
calmodulin binding,
ubiquitin-protein ligase activity,
zinc ion binding |
cytoplasm,
cytoskeleton,
integral to membrane,
nucleus |
interspecies interaction between organisms |
| Secreted frizzled-related protein 2 precursor |
unclassified |
fibronectin binding,
integrin binding |
extracellular matrix,
extracellular space |
positive regulation of cell adhesion mediated by integrin,
patterning of blood vessels,
sclerotome development,
positive regulation of cell growth,
negative regulation of cell proliferation,
positive regulation of anti-apoptosis,
positive regulation of apoptosis,
cell-cell signaling,
Wnt receptor signaling pathway,
positive regulation of angiogenesis,
negative regulation of cell migration,
dermatome development,
positive regulation of cell proliferation,
outflow tract morphogenesis,
hemopoietic stem cell proliferation,
negative regulation of cell growth,
negative regulation of peptidyl-tyrosine phosphorylation,
cardiac left ventricle morphogenesis,
regulation of stem cell division,
negative regulation of gene expression |
| Atrial natriuretic peptide clearance receptor precursor |
receptor activity |
peptide receptor activity, G-protein coupled,
natriuretic peptide receptor activity |
integral to membrane |
regulation of blood pressure,
osteoclast proliferation,
diuresis,
skeletal system development,
regulation of osteoblast proliferation |
| Retinoic acid-induced protein 1 |
unclassified |
zinc ion binding,
protein binding |
cytoplasm,
nucleus |
|
| Retinoblastoma-binding protein 5 |
|
promoter binding,
protein binding |
MLL1 complex |
regulation of transcription,
transcription,
response to estrogen stimulus,
histone H3-K4 methylation |
| Calcium-dependent secretion activator 2 |
|
metal ion binding,
lipid binding |
cell junction,
cytoplasmic vesicle membrane |
exocytosis,
protein transport |
| Secretion-regulating guanine nucleotide exchange factor |
|
Ran guanyl-nucleotide exchange factor activity,
protein binding |
cytoplasm,
nucleus |
negative regulation of protein secretion,
signal transduction |
| retr-1 |
|
hydrolase activity |
|
|
| Protein claret segregational |
|
minus-end-directed microtubule motor activity,
ATP binding,
protein homodimerization activity |
spindle,
microtubule |
minus-end directed microtubule sliding,
regulation of mitotic spindle elongation,
mitotic spindle elongation,
mitotic centrosome separation,
cell division,
spindle assembly involved in female meiosis,
distributive segregation,
microtubule bundle formation,
spindle assembly involved in mitosis |
| Protein retinal degeneration B |
|
phosphatidylinositol transporter activity,
metal ion binding,
phosphatidylcholine transmembrane transporter activity |
subrhabdomeral cisterna,
integral to membrane |
sensory perception of smell,
calcium ion transport,
deactivation of rhodopsin mediated signaling,
phosphoinositide metabolic process,
rhodopsin mediated signaling pathway |
| Retinoblastoma family protein |
|
promoter binding,
transcription factor binding |
Myb complex,
Rb-E2F complex,
chromatin |
negative regulation of cell proliferation,
negative regulation of apoptosis,
negative regulation of DNA replication,
transcription,
DNA endoreduplication,
G1 phase of mitotic cell cycle,
negative regulation of S phase of mitotic cell cycle,
endomitotic cell cycle,
negative regulation of transcription from RNA polymerase II promoter,
regulation of DNA binding,
eggshell chorion gene amplification |
