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NameDescriptionMolecular FunctionCellular ComponentBiological Process
Beta-arrestin 2 Beta-arrestin 2 angiotensin receptor binding,
ubiquitin protein ligase binding
plasma membrane,
coated pit,
cytoplasmic membrane-bounded vesicle,
nucleus
positive regulation of ERK1 and ERK2 cascade,
negative regulation of protein ubiquitination,
sensory perception,
G-protein coupled receptor internalization,
cell chemotaxis,
desensitization of G-protein coupled receptor protein signaling pathway by arrestin,
transcription from RNA polymerase II promoter,
negative regulation of NF-kappaB transcription factor activity,
negative regulation of signal transduction,
proteasomal ubiquitin-dependent protein catabolic process,
protein ubiquitination,
negative regulation of natural killer cell mediated cytotoxicity,
protein transport,
signal transduction,
transforming growth factor beta receptor signaling pathway
Beta-arrestin 1 Adapter molecule insulin-like growth factor receptor binding,
enzyme inhibitor activity,
angiotensin receptor binding,
promoter binding,
ubiquitin protein ligase binding,
GTPase activator activity,
transcription factor binding
plasma membrane,
pseudopodium,
coated pit,
soluble fraction,
membrane fraction,
chromatin,
cytoplasmic membrane-bounded vesicle,
nucleus
positive regulation of ERK1 and ERK2 cascade,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
histone H4 acetylation,
negative regulation of protein ubiquitination,
sensory perception,
G-protein coupled receptor internalization,
stress fiber assembly,
transcription from RNA polymerase II promoter,
negative regulation of interleukin-8 production,
negative regulation of NF-kappaB transcription factor activity,
negative regulation of signal transduction,
proteasomal ubiquitin-dependent protein catabolic process,
protein ubiquitination,
protein transport,
post-Golgi vesicle-mediated transport,
positive regulation of histone acetylation,
positive regulation of Rho protein signal transduction,
negative regulation of interleukin-6 production
Restin Unclassified nucleic acid binding,
microtubule plus-end binding,
protein homodimerization activity,
microtubule binding,
zinc ion binding
intermediate filament,
kinetochore,
cytoplasmic microtubule,
microtubule,
endosome
mitosis

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