a database of S/T/Y phosphorylation sites
Statistics
:
Instances
42.914
Kinases
299
References
3.657
Sequences
11.224
Substrates
8.698
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Name
Description
Molecular Function
Cellular Component
Biological Process
Beta-arrestin 2
Beta-arrestin 2
angiotensin receptor binding
,
ubiquitin protein ligase binding
plasma membrane
,
coated pit
,
cytoplasmic membrane-bounded vesicle
,
nucleus
positive regulation of ERK1 and ERK2 cascade
,
negative regulation of protein ubiquitination
,
sensory perception
,
G-protein coupled receptor internalization
,
cell chemotaxis
,
desensitization of G-protein coupled receptor protein signaling pathway by arrestin
,
transcription from RNA polymerase II promoter
,
negative regulation of NF-kappaB transcription factor activity
,
negative regulation of signal transduction
,
proteasomal ubiquitin-dependent protein catabolic process
,
protein ubiquitination
,
negative regulation of natural killer cell mediated cytotoxicity
,
protein transport
,
signal transduction
,
transforming growth factor beta receptor signaling pathway
Beta-arrestin 1
Adapter molecule
insulin-like growth factor receptor binding
,
enzyme inhibitor activity
,
angiotensin receptor binding
,
promoter binding
,
ubiquitin protein ligase binding
,
GTPase activator activity
,
transcription factor binding
plasma membrane
,
pseudopodium
,
coated pit
,
soluble fraction
,
membrane fraction
,
chromatin
,
cytoplasmic membrane-bounded vesicle
,
nucleus
positive regulation of ERK1 and ERK2 cascade
,
positive regulation of gene-specific transcription from RNA polymerase II promoter
,
histone H4 acetylation
,
negative regulation of protein ubiquitination
,
sensory perception
,
G-protein coupled receptor internalization
,
stress fiber assembly
,
transcription from RNA polymerase II promoter
,
negative regulation of interleukin-8 production
,
negative regulation of NF-kappaB transcription factor activity
,
negative regulation of signal transduction
,
proteasomal ubiquitin-dependent protein catabolic process
,
protein ubiquitination
,
protein transport
,
post-Golgi vesicle-mediated transport
,
positive regulation of histone acetylation
,
positive regulation of Rho protein signal transduction
,
negative regulation of interleukin-6 production
Restin
Unclassified
nucleic acid binding
,
microtubule plus-end binding
,
protein homodimerization activity
,
microtubule binding
,
zinc ion binding
intermediate filament
,
kinetochore
,
cytoplasmic microtubule
,
microtubule
,
endosome
mitosis