| Name | Description | Molecular Function | Cellular Component | Biological Process |
|---|
| Sp110 |
DNA binding |
DNA binding |
nucleus |
apoptosis,
regulation of transcription,
induction of apoptosis,
transcription,
innate immune response,
response to bacterium |
| Sp1 |
Transcription factor Sp1 |
RNA polymerase II transcription factor activity,
histone deacetylase binding,
promoter binding,
protein C-terminus binding,
protein homodimerization activity,
enhancer binding,
transcription activator activity,
double-stranded DNA binding,
zinc ion binding,
sequence-specific DNA binding transcription factor activity |
cytoplasm,
nucleus |
enucleate erythrocyte differentiation,
embryonic placenta development,
ossification,
embryonic skeletal system development,
megakaryocyte differentiation,
embryonic camera-type eye morphogenesis,
lung development,
transcription,
definitive hemopoiesis,
positive regulation by host of viral transcription,
embryonic process involved in female pregnancy,
positive regulation of transcription from RNA polymerase II promoter, global,
liver development,
trophectodermal cell differentiation |
| LASP1 |
Cytoskeletal protein |
ion transmembrane transporter activity,
SH3/SH2 adaptor activity,
actin binding,
zinc ion binding,
actin filament binding |
focal adhesion,
cortical actin cytoskeleton |
|
| Cofactor required for Sp1 transcriptional activation subunit 2 |
Transcription regulatory protein |
ligand-dependent nuclear receptor transcription coactivator activity,
RNA polymerase II transcription mediator activity,
receptor activity,
vitamin D receptor binding,
thyroid hormone receptor binding,
protein binding |
mediator complex |
transcription from RNA polymerase II promoter,
regulation of transcription from RNA polymerase II promoter,
androgen receptor signaling pathway,
transcription initiation from RNA polymerase II promoter,
positive regulation of transcription from RNA polymerase II promoter |
| USP19 |
Enzyme: ubiquitin hydrolase |
ubiquitin thiolesterase activity,
cysteine-type peptidase activity,
zinc ion binding |
integral to membrane,
endoplasmic reticulum membrane |
proteasomal ubiquitin-dependent protein catabolic process |
| DUSP16 |
phosphoprotein phosphatase activity |
protein tyrosine phosphatase activity,
MAP kinase tyrosine/serine/threonine phosphatase activity |
cytoplasmic membrane-bounded vesicle,
nucleus |
inactivation of MAPK activity,
protein amino acid dephosphorylation,
MAPK phosphatase export from nucleus, leptomycin B sensitive,
MAPK export from nucleus |
| DUSP10 |
phosphoprotein phosphatase activity |
protein tyrosine phosphatase activity,
MAP kinase tyrosine/serine/threonine phosphatase activity |
cytoplasm,
nucleus |
JNK cascade,
protein amino acid dephosphorylation |
| SP100 |
unclassified |
DNA binding,
identical protein binding,
chromo shadow domain binding,
general transcriptional repressor activity,
transcription corepressor activity,
kinase binding,
protein homodimerization activity,
transcription coactivator activity,
protein binding |
cytoplasm,
nuclear periphery,
PML body,
chromosome,
nucleolus,
nucleus |
positive regulation of transcription, DNA-dependent,
response to interferon-gamma,
response to cytokine stimulus,
interspecies interaction between organisms,
type I interferon-mediated signaling pathway,
negative regulation of transcription factor activity,
retinoic acid receptor signaling pathway,
negative regulation of viral transcription,
positive regulation of transcription factor activity,
response to type I interferon,
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator,
negative regulation of cellular component movement,
interferon-gamma-mediated signaling pathway,
response to retinoic acid,
negative regulation of transcription from RNA polymerase II promoter |
| Gorasp1 |
Golgi peripheral membrane protein |
protein binding |
Golgi apparatus,
membrane |
Golgi organization,
protein transport |
| USP14 |
Enzyme: Hydrolase |
ubiquitin thiolesterase activity,
cysteine-type peptidase activity |
plasma membrane,
cytoplasm,
synaptosome,
soluble fraction,
proteasome complex |
synaptic transmission,
ubiquitin-dependent protein catabolic process |
| USP15 |
Enzyme: Hydrolase |
ubiquitin-specific protease activity,
ubiquitin thiolesterase activity,
cysteine-type endopeptidase activity,
protein binding |
|
ubiquitin-dependent protein catabolic process,
protein deubiquitination |
| USP11 |
|
ubiquitin-specific protease activity,
ubiquitin thiolesterase activity,
cysteine-type endopeptidase activity,
protein binding |
cytoplasm,
nucleus |
ubiquitin-dependent protein catabolic process,
protein deubiquitination |
| USP13 |
|
ubiquitin-specific protease activity,
ubiquitin thiolesterase activity,
cysteine-type endopeptidase activity,
zinc ion binding,
protein binding |
|
ubiquitin-dependent protein catabolic process |
