a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	c-myc (Myc proto-oncogene protein (c-myc))
Seq-ID:	P01106 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-25075   MAX_HUMAN MINT-6628157   VE7_HPV16 MINT-7040788   AXN1_HUMAN MINT-7306800   BIN1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process transcription activator activity, E-box binding, sequence-specific DNA binding transcription factor activity nucleolus branching involved in ureteric bud morphogenesis, cellular iron ion homeostasis, cell cycle arrest, response to drug, cell proliferation, positive regulation of metanephric cap mesenchymal cell proliferation, regulation of telomere maintenance
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	58	DIWKKFELLPTPPLSPSRRSG	GSK-3_group	11018017	LTP	1.00	MOD_GSK3_1	-	Myc_N	0.38	-	low
T	58	DIWKKFELLPTPPLSPSRRSG	GSK-3_beta	14563837	LTP	1.00	MOD_GSK3_1	-	Myc_N	0.38	-	low
T	58	DIWKKFELLPTPPLSPSRRSG	GSK-3_alpha	14563837	LTP	1.00	MOD_GSK3_1	-	Myc_N	0.38	-	low
T	58	DIWKKFELLPTPPLSPSRRSG	GSK-3_group	15150404	LTP	1.00	MOD_GSK3_1	-	Myc_N	0.38	-	low
T	58	DIWKKFELLPTPPLSPSRRSG	-	17081983	HTP	1.00	MOD_GSK3_1	-	Myc_N	0.38	-	low
T	58	DIWKKFELLPTPPLSPSRRSG	-	18669648	HTP	1.00	MOD_GSK3_1	-	Myc_N	0.38	-	low
S	62	KFELLPTPPLSPSRRSGLCSP	MAPK1	1651323	LTP	1.00	MOD_ProDKin_1	-	Myc_N	0.37	-	low
S	62	KFELLPTPPLSPSRRSGLCSP	-	17081983	HTP	1.00	MOD_ProDKin_1	-	Myc_N	0.37	-	low
S	62	KFELLPTPPLSPSRRSGLCSP	-	18220336	HTP	1.00	MOD_ProDKin_1	-	Myc_N	0.37	-	low
S	62	KFELLPTPPLSPSRRSGLCSP	-	18669648	HTP	1.00	MOD_ProDKin_1	-	Myc_N	0.37	-	low
S	71	LSPSRRSGLCSPSYVAVTPFS	-	18669648	HTP	0.92		-	Myc_N	0.33	-	low

Substrate:	c-myc (Myc proto-oncogene protein (c-myc))
Seq-ID:	P01108 [Mus musculus]
Download:	fasta csv
Interaction Network(s):	-
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process transcription activator activity spindle, nuclear body, nucleolus, axon B cell apoptosis, branching involved in ureteric bud morphogenesis, negative regulation of gene-specific transcription from RNA polymerase II promoter, skeletal system morphogenesis, cellular response to protein stimulus, response to alkaloid, detection of mechanical stimulus involved in sensory perception of sound, positive regulation of B cell apoptosis, release of cytochrome c from mitochondria, activation of caspase activity, protein processing, negative regulation of survival gene product expression, response to radiation, negative regulation of protein binding, induction of apoptosis by intracellular signals, middle ear morphogenesis, activation of pro-apoptotic gene products, positive regulation of transcription from RNA polymerase II promoter, DNA fragmentation involved in apoptotic nuclear change, pigmentation, positive regulation of metanephric cap mesenchymal cell proliferation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	58	DIWKKFELLPTPPLSPSRRSG	-	15048125	LTP	0.94		-	Myc_N	0.39	-	medium
S	62	KFELLPTPPLSPSRRSGLCSP	-	15048125	LTP	0.94		-	Myc_N	0.38	-	medium
T	358	SDTEENDKRRTHNVLERQRRN	PAK2	14749374	LTP	1.00		-	HLH	0.87	-	medium
S	373	ERQRRNELKRSFFALRDQIPE	PAK2	14749374	LTP	1.00		-	HLH	0.52	-	medium
T	400	APKVVILKKATAYILSIQADE	PAK2	14749374	LTP	0.91		-	HLH	0.36	-	medium