Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate: ACK-1 (Tyrosine kinase)

Seq-ID: O54967 [Mus musculus]

Download: fasta csv

Interaction Network(s): -

External Source(s):

MINT Interaction(s): -

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

magnesium ion binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
protein binding neuronal cell body,
dendrite,
adherens junction,
axon,
growth cone protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

Y 842 TTQSFASDPKYATPQVIQAPG - 14739304
HTP

0.12
- -
0.84
- medium

Substrate: ACK-1 (Tyrosine kinase)

Seq-ID: Q07912 [Homo sapiens]

Download: fasta csv

Interaction Network(s): -

External Source(s):

MINT Interaction(s):
[show]

MINT-62876   GRB2_HUMAN
MINT-62877   NCK1_HUMAN
MINT-62878   SYNJ1_HUMAN
MINT-64702   RL18A_HUMAN
MINT-64703   SFRS5_HUMAN
MINT-7104372   CRK_HUMAN
MINT-7104436   BCAR1_HUMAN
MINT-7983409   CLH1_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

magnesium ion binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
GTPase inhibitor activity,
protein binding adherens junction positive regulation of peptidyl-tyrosine phosphorylation,
protein amino acid phosphorylation,
small GTPase mediated signal transduction

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 102 HHSQSTFRKTSPAPGGPAGEG - 18669648
HTP

0.16
- -
0.81
- -

Y 284 MRALPQNDDHYVMQEHRKVPF TNK2 14506255
LTP

1.00
- TyrKc
0.27
1U46 32.75%

Y 284 MRALPQNDDHYVMQEHRKVPF TNK2 16472662
LTP

1.00
- TyrKc
0.27
1U46 32.75%

Y 518 QHLGGVKKPTYDPVSEDQDPL - 15592455
HTP

1.00
- -
0.76
- -

Y 518 QHLGGVKKPTYDPVSEDQDPL - 18083107
HTP

1.00
- -
0.76
- -

Y 826 TTQSFASDPKYATPQVIQAPG - 12522270
HTP

0.55
- -
0.82
- -

Y 826 TTQSFASDPKYATPQVIQAPG - 17081983
HTP

0.55
- -
0.82
- -

Y 857 RDGKKVSSTHYYLLPERPSYL - 12522270
HTP

0.79
- -
0.56
- -

Y 858 DGKKVSSTHYYLLPERPSYLE - 12522270
HTP

0.84
- -
0.54
- -

Substrate: ACK-1 (Tyrosine kinase)

Seq-ID: ENSP00000371341 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s): -

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

magnesium ion binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
GTPase inhibitor activity,
protein binding adherens junction positive regulation of peptidyl-tyrosine phosphorylation,
protein amino acid phosphorylation,
small GTPase mediated signal transduction

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 212 VVRRGEWDAPSGKTVSVAVKC - 17081983
HTP

0.10
- TyrKc
0.33
1U46 72.95%

Y 905 TTQSFASDPKYATPQVIQAPG - 17081983
HTP

1.00
- -
0.83
- -

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	102	HHSQSTFRKTSPAPGGPAGEG	-	18669648	HTP	0.16	-	-	0.81	-	-
Y	284	MRALPQNDDHYVMQEHRKVPF	TNK2	14506255	LTP	1.00	-	TyrKc	0.27	1U46	32.75%
Y	284	MRALPQNDDHYVMQEHRKVPF	TNK2	16472662	LTP	1.00	-	TyrKc	0.27	1U46	32.75%
Y	518	QHLGGVKKPTYDPVSEDQDPL	-	15592455	HTP	1.00	-	-	0.76	-	-
Y	518	QHLGGVKKPTYDPVSEDQDPL	-	18083107	HTP	1.00	-	-	0.76	-	-
Y	826	TTQSFASDPKYATPQVIQAPG	-	12522270	HTP	0.55	-	-	0.82	-	-
Y	826	TTQSFASDPKYATPQVIQAPG	-	17081983	HTP	0.55	-	-	0.82	-	-
Y	857	RDGKKVSSTHYYLLPERPSYL	-	12522270	HTP	0.79	-	-	0.56	-	-
Y	858	DGKKVSSTHYYLLPERPSYLE	-	12522270	HTP	0.84	-	-	0.54	-	-

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	212	VVRRGEWDAPSGKTVSVAVKC	-	17081983	HTP	0.10		-	TyrKc	0.33	1U46	72.95%
Y	905	TTQSFASDPKYATPQVIQAPG	-	17081983	HTP	1.00		-	-	0.83	-	-