Substrate: LAT (Adaptor molecule involved in the TCR signal pathway)
Seq-ID: O43561 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-3382436   GRB2_HUMAN
MINT-3382457   SOS1_MOUSE
MINT-3382488   ZAP70_HUMAN
MINT-6794135   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3/SH2 adaptor activity immunological synapse,
integral to membrane,
membrane raft		 calcium-mediated signaling,
integrin-mediated signaling pathway,
mast cell degranulation,
regulation of T cell activation,
Ras protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 38 HCHRLPGSYDSTSSDSLYPRG - 15659558
HTP
1.00
 - -
0.37
 - medium
T 39 CHRLPGSYDSTSSDSLYPRGI - 15659558
HTP
1.00
 - -
0.39
 - medium
T 39 CHRLPGSYDSTSSDSLYPRGI - 18088087
HTP
1.00
 - -
0.39
 - medium
S 40 HRLPGSYDSTSSDSLYPRGIQ - 15659558
HTP
1.00
 - -
0.41
 - medium
S 84 SQPDLLPIPRSPQPLGGSHRT - 15659558
HTP
1.00
 - -
0.74
 - medium
S 84 SQPDLLPIPRSPQPLGGSHRT - 18088087
HTP
1.00
 - -
0.74
 - medium
S 101 SHRTPSSRRDSDGANSVASYE - 18088087
HTP
1.00
 - -
0.79
 - medium
S 109 RDSDGANSVASYENEGASGIR - 18088087
HTP
1.00
 - -
0.70
 - medium
Y 220 AEASLDGSREYVNVSQELHPG - 15659558
HTP
1.00
 GRAP2 SH2;
GRB2 SH2;
PIK3R1 SH2;
PLCG1 SH2;
VAV1 SH2		 -
0.71
 - medium
S 224 LDGSREYVNVSQELHPGAAKT - 15659558
HTP
1.00
 - -
0.73
 - medium
S 224 LDGSREYVNVSQELHPGAAKT - 18088087
HTP
1.00
 - -
0.73
 - medium

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