Phospho.ELM Result

a database of S/T/Y phosphorylation sites

LAT (Adaptor molecule involved in the TCR signal pathway)

Seq-ID:

O54957 [Mus musculus]

Download:

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

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Molecular Function	Cellular Component	Biological Process
SH3/SH2 adaptor activity, receptor signaling protein activity	integral to plasma membrane, immunological synapse	calcium-mediated signaling, integrin-mediated signaling pathway, gene expression, cellular defense response, inflammatory response, mast cell degranulation, regulation of T cell activation, Ras protein signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	136	DEDEDDYPNGYLVVLPDSSPA	-	10811803	LTP	0.00	PLCG_group SH2	-	0.77	-	low
Y	136	DEDEDDYPNGYLVVLPDSSPA	ZAP70	11368773	LTP	0.00	PLCG_group SH2	-	0.77	-	low
Y	136	DEDEDDYPNGYLVVLPDSSPA	ZAP70	11457888	LTP	0.00	PLCG_group SH2	-	0.77	-	low
Y	175	SAFSVESCEDYVNVPESEESA	-	10811803	LTP	1.00	GRAP2 SH2; GRB2 SH2; VAV_group SH2	-	0.71	-	low
Y	175	SAFSVESCEDYVNVPESEESA	ZAP70	11368773	LTP	1.00	GRAP2 SH2; GRB2 SH2; VAV_group SH2	-	0.71	-	low
Y	195	AEASLDGSREYVNVSPEQQPV	-	10811803	LTP	1.00	GRAP2 SH2; GRB2 SH2; VAV_group SH2	-	0.83	-	low
Y	195	AEASLDGSREYVNVSPEQQPV	ZAP70	11368773	LTP	1.00	GRAP2 SH2; GRB2 SH2; VAV_group SH2	-	0.83	-	low
Y	235	EGVDGEEAPDYENLQELN	-	10811803	LTP	1.00	GRB2 SH2; VAV_group SH2	-	0.90	-	low
Y	235	EGVDGEEAPDYENLQELN	ZAP70	11368773	LTP	1.00	GRB2 SH2; VAV_group SH2	-	0.90	-	low