Substrate: CD74 (CD antigen)
Seq-ID: P04441 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
MHC class II protein binding,
cytokine receptor activity		 external side of plasma membrane,
integral to plasma membrane,
Golgi apparatus,
lysosome,
multivesicular body,
endoplasmic reticulum		 positive regulation of peptidyl-tyrosine phosphorylation,
positive regulation of ERK1 and ERK2 cascade,
protein complex assembly,
negative regulation of apoptosis,
positive thymic T cell selection,
prostaglandin biosynthetic process,
positive regulation of T cell differentiation,
negative regulation of DNA damage response, signal transduction by p53 class mediator,
chaperone mediated protein folding requiring cofactor,
negative regulation of T cell differentiation,
intracellular protein transport,
antigen processing and presentation of exogenous peptide antigen via MHC class II,
negative thymic T cell selection,
defense response,
cell proliferation,
immunoglobulin mediated immune response,
positive regulation of cytokine-mediated signaling pathway
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 9   MDDQRDLISNHEQLPILGN - 19144319
HTP
1.00
 - MHC2-interact
0.52
 - medium

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