Substrate: NPM (nucleophosmin (nucleolar phosphoprotein B23) (from PhosphoBase))
Seq-ID: P06748 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-48882   M3K14_HUMAN
MINT-74886   P53_HUMAN
MINT-75016   PTBP1_HUMAN
MINT-75017   SFRS1_HUMAN
MINT-3089429   E2AK2_HUMAN
MINT-3296152   1433Z_HUMAN
MINT-4544864   AP2A_HUMAN
MINT-4544899   HDAC1_HUMAN
MINT-4544944   HDAC2_HUMAN
MINT-6541788   SENP3_HUMAN
MINT-7041169   HABP4_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Tat protein binding,
histone binding,
ribosomal small subunit binding,
protein heterodimerization activity,
ribosomal large subunit binding,
protein homodimerization activity,
unfolded protein binding,
transcription coactivator activity,
NF-kappaB binding		 spindle pole centrosome response to stress,
negative regulation of cell proliferation,
negative regulation of centrosome duplication,
nucleosome assembly,
anti-apoptosis,
cell aging,
signal transduction,
protein oligomerization,
intracellular protein transport,
centrosome cycle,
interspecies interaction between organisms,
positive regulation of NF-kappaB transcription factor activity,
ribosome assembly
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 4        MEDSMDMDMSPLRP PLK1 15190079
LTP
1.00
 MOD_PLK
 - -
0.63
 --
S 4        MEDSMDMDMSPLRP - 17081983
HTP
1.00
 MOD_PLK
 - -
0.63
 --
S 10  MEDSMDMDMSPLRPQNYLFG - 17081983
HTP
1.00
 - -
0.41
 --
Y 67 LHIVEAEAMNYEGSPIKVTLA - 18669648
HTP
0.96
 - Nucleoplasmin
0.40
 --
S 70 VEAEAMNYEGSPIKVTLATLK - 16565220
HTP
0.92
 - Nucleoplasmin
0.40
 --
S 70 VEAEAMNYEGSPIKVTLATLK - 17081983
HTP
0.92
 - Nucleoplasmin
0.40
 --
S 70 VEAEAMNYEGSPIKVTLATLK - 17287340
HTP
0.92
 - Nucleoplasmin
0.40
 --
S 70 VEAEAMNYEGSPIKVTLATLK - 18220336
HTP
0.92
 - Nucleoplasmin
0.40
 --
S 70 VEAEAMNYEGSPIKVTLATLK - 18669648
HTP
0.92
 - Nucleoplasmin
0.40
 --
T 75 MNYEGSPIKVTLATLKMSVQP - 18669648
HTP
1.00
 - Nucleoplasmin
0.45
 --
T 78 EGSPIKVTLATLKMSVQPTVS - 18669648
HTP
1.00
 - Nucleoplasmin
0.45
 --
S 88 TLKMSVQPTVSLGGFEITPPV - 18220336
HTP
0.95
 - Nucleoplasmin
0.48
 --
T 95 PTVSLGGFEITPPVVLRLKCG - 16041368
LTP
0.98
 - Nucleoplasmin
0.41
 --
T 95 PTVSLGGFEITPPVVLRLKCG - 18220336
HTP
0.98
 - Nucleoplasmin
0.41
 --
T 95 PTVSLGGFEITPPVVLRLKCG - 18669648
HTP
0.98
 - Nucleoplasmin
0.41
 --
S 125 HLVAVEEDAESEDEEEEDVKL - 3944116
LTP
1.00
 - Nucleoplasmin
0.78
 --
S 125 HLVAVEEDAESEDEEEEDVKL - 17081983
HTP
1.00
 - Nucleoplasmin
0.78
 --
S 125 HLVAVEEDAESEDEEEEDVKL - 17287340
HTP
1.00
 - Nucleoplasmin
0.78
 --
S 125 HLVAVEEDAESEDEEEEDVKL - 18220336
HTP
1.00
 - Nucleoplasmin
0.78
 --
S 125 HLVAVEEDAESEDEEEEDVKL - 18669648
HTP
1.00
 - Nucleoplasmin
0.78
 --
S 137 DEEEEDVKLLSISGKRSAPGG - 17287340
HTP
0.61
 - Nucleoplasmin
0.78
 --
S 137 DEEEEDVKLLSISGKRSAPGG - 18669648
HTP
0.61
 - Nucleoplasmin
0.78
 --
S 139 EEEDVKLLSISGKRSAPGGGS - 18669648
HTP
0.98
 - Nucleoplasmin
0.75
 --
T 199 KAPVKKSIRDTPAKNAQKSNQ - 7213797
LTP
1.00
 MOD_CDK_SPxK_1
 - Nucleoplasmin
0.83
 --
T 199 KAPVKKSIRDTPAKNAQKSNQ - 16083285
HTP
1.00
 MOD_CDK_SPxK_1
 - Nucleoplasmin
0.83
 --
T 199 KAPVKKSIRDTPAKNAQKSNQ CDK1 12058066
LTP
1.00
 MOD_CDK_SPxK_1
 - Nucleoplasmin
0.83
 --
T 199 KAPVKKSIRDTPAKNAQKSNQ CDK1 15190079
LTP
1.00
 MOD_CDK_SPxK_1
 - Nucleoplasmin
0.83
 --
T 199 KAPVKKSIRDTPAKNAQKSNQ - 17081983
HTP
1.00
 MOD_CDK_SPxK_1
 - Nucleoplasmin
0.83
 --
T 199 KAPVKKSIRDTPAKNAQKSNQ - 17287340
HTP
1.00
 MOD_CDK_SPxK_1
 - Nucleoplasmin
0.83
 --
T 219 QNGKDSKPSSTPRSKGQESFK - 12058066
LTP
0.48
 - -
0.89
 --
S 227 SSTPRSKGQESFKKQEKTPKT PKC_group 1446684
LTP
1.00
 - -
0.89
 --
T 234 GQESFKKQEKTPKTPKGPSSV CDK1 14670079
LTP
0.97
 - -
0.86
 --
T 234 GQESFKKQEKTPKTPKGPSSV - 17287340
HTP
0.97
 - -
0.86
 --
T 234 GQESFKKQEKTPKTPKGPSSV - 18669648
HTP
0.97
 - -
0.86
 --
T 237 SFKKQEKTPKTPKGPSSVEDI CDK1 14670079
LTP
1.00
 - -
0.85
 --
T 237 SFKKQEKTPKTPKGPSSVEDI - 17287340
HTP
1.00
 - -
0.85
 --
T 237 SFKKQEKTPKTPKGPSSVEDI - 18669648
HTP
1.00
 - -
0.85
 --
S 243 KTPKTPKGPSSVEDIKAKMQA - 18669648
HTP
1.00
 - -
0.85
 --
S 254 VEDIKAKMQASIEKGGSLPKV - 16565220
HTP
1.00
 - -
0.71
 --
S 254 VEDIKAKMQASIEKGGSLPKV - 17081983
HTP
1.00
 - -
0.71
 --
S 254 VEDIKAKMQASIEKGGSLPKV - 18669648
HTP
1.00
 - -
0.71
 --
S 260 KMQASIEKGGSLPKVEAKFIN - 17287340
HTP
0.97
 - -
0.58
 --
S 260 KMQASIEKGGSLPKVEAKFIN - 18669648
HTP
0.97
 - -
0.58
 --
T 279 INYVKNCFRMTDQEAIQDLWQ - 18220336
HTP
0.97
 - -
0.40
 --
T 279 INYVKNCFRMTDQEAIQDLWQ - 18669648
HTP
0.97
 - -
0.40
 --

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