Substrate: RET (Probable receptor with tyrosine-protein kinase activity; important for development.)
Seq-ID: P07949 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-60970   CBL_HUMAN
MINT-60975   GRB2_HUMAN
MINT-60981   SHC1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
calcium ion binding,
transmembrane receptor protein tyrosine kinase activity,
ATP binding		 integral to membrane protein amino acid phosphorylation,
posterior midgut development,
homophilic cell adhesion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 687 RRPAQAFPVSYSSSGARRPSL RET 11470823
LTP
0.12
 - -
0.36
 --
Y 687 RRPAQAFPVSYSSSGARRPSL RET 8621380
LTP
0.12
 - -
0.36
 --
S 696 SYSSSGARRPSLDSMENQVSV - 11886862
LTP
1.00
 - -
0.40
 --
Y 791 QVNHPHVIKLYGACSQDGPLL - 15753368
LTP
0.19
 - TyrKc
0.19
 2IVS 28.82%
Y 806 QDGPLLLIVEYAKYGSLRGFL RET 14711813
LTP
1.00
 - TyrKc
0.07
 2IVS 24.45%
Y 809 PLLLIVEYAKYGSLRGFLRES RET 14711813
LTP
1.00
 - TyrKc
0.06
 2IVS 28.38%
Y 826 LRESRKVGPGYLGSGGSRNSS - 11470823
LTP
1.00
 - TyrKc
0.46
 2IVS 29.26%
Y 826 LRESRKVGPGYLGSGGSRNSS RET 8621380
LTP
1.00
 - TyrKc
0.46
 2IVS 29.26%
S 891 LVAEGRKMKISDFGLSRDVYE - 15753368
LTP
1.00
 - TyrKc
0.20
 2IVS 3.28%
Y 900 ISDFGLSRDVYEEDSYVKRSQ RET 14711813
LTP
1.00
 - TyrKc
0.25
 2IVS 24.89%
Y 905 LSRDVYEEDSYVKRSQGRIPV RET 14711813
LTP
1.00
 - TyrKc
0.27
 2IVS 27.07%
Y 981 ERPDNCSEEMYRLMLQCWKQE RET 14711813
LTP
1.00
 SH2B1 SH2 TyrKc
0.34
 2IVS 19.65%
Y 981 ERPDNCSEEMYRLMLQCWKQE RET 14766744
LTP
1.00
 SH2B1 SH2 TyrKc
0.34
 2IVS 19.65%
Y 1015 LEKMMVKRRDYLDLAASTPSD - 11470823
LTP
1.00
 PLCG1 SH2;
SHC1 SH2;
Src SH2		 -
0.33
 --
Y 1015 LEKMMVKRRDYLDLAASTPSD RET 14981541
LTP
1.00
 PLCG1 SH2;
SHC1 SH2;
Src SH2		 -
0.33
 --
Y 1029 AASTPSDSLIYDDGLSEEETP - 11470823
LTP
1.00
 Src SH2 -
0.51
 --
Y 1029 AASTPSDSLIYDDGLSEEETP RET 8621380
LTP
1.00
 Src SH2 -
0.51
 --
Y 1029 AASTPSDSLIYDDGLSEEETP RET 14766744
LTP
1.00
 Src SH2 -
0.51
 --
Y 1062 LPSTWIENKLYGMSDPNWPGE - 11470823
LTP
0.19
 FRS2 PTB;
IRS1 PTB;
PIK3R1 SH2;
SHC1 PTB;
SHC1 SH2;
SHC3 PTB;
SHC3 SH2		 -
0.43
 --
Y 1062 LPSTWIENKLYGMSDPNWPGE RET 14711813
LTP
0.19
 FRS2 PTB;
IRS1 PTB;
PIK3R1 SH2;
SHC1 PTB;
SHC1 SH2;
SHC3 PTB;
SHC3 SH2		 -
0.43
 --
Y 1062 LPSTWIENKLYGMSDPNWPGE RET 14981541
LTP
0.19
 FRS2 PTB;
IRS1 PTB;
PIK3R1 SH2;
SHC1 PTB;
SHC1 SH2;
SHC3 PTB;
SHC3 SH2		 -
0.43
 --
Y 1090 ADGTNTGFPRYPNDSVYANWM RET 14711813
LTP
0.16
 GRB2 SH2 -
0.41
 --
Y 1096 GFPRYPNDSVYANWMLSPSAA - 11470823
LTP
1.00
 GRB2 SH2 -
0.33
 --
Y 1096 GFPRYPNDSVYANWMLSPSAA RET 8621380
LTP
1.00
 GRB2 SH2 -
0.33
 --
Y 1096 GFPRYPNDSVYANWMLSPSAA RET 14711813
LTP
1.00
 GRB2 SH2 -
0.33
 --

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