Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Pleckstrin (pleckstrin (platelet p47 protein) (from PhosphoBase))

Seq-ID:

P08567 [Homo sapiens]

Download:

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
phosphatidylinositol-3,4-bisphosphate binding, protein kinase C binding, protein homodimerization activity	extracellular region, membrane fraction, cytosol, ruffle membrane, soluble fraction	negative regulation of calcium-mediated signaling, vesicle docking involved in exocytosis, cortical actin cytoskeleton organization, negative regulation of inositol phosphate biosynthetic process, positive regulation of actin filament depolymerization, actin cytoskeleton reorganization, positive regulation of actin filament bundle assembly, integrin-mediated signaling pathway, protein kinase C signaling cascade, inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway, protein secretion by platelet, hemopoietic progenitor cell differentiation, positive regulation of platelet activation, platelet aggregation, phosphoinositide metabolic process, positive regulation of inositol-polyphosphate 5-phosphatase activity, positive regulation of integrin activation, regulation of cell diameter, ruffle organization, thrombin receptor signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	113	IEGGQKFARKSTRRSIRLPET	-	7559487	LTP	1.00	-	-	0.37	-	medium
S	113	IEGGQKFARKSTRRSIRLPET	PKC_group	8615792	LTP	1.00	-	-	0.37	-	medium
S	113	IEGGQKFARKSTRRSIRLPET	PKC_alpha	8615792	LTP	1.00	-	-	0.37	-	medium
T	114	EGGQKFARKSTRRSIRLPETI	PKC_group	7559487	LTP	1.00	-	-	0.38	-	medium
S	117	QKFARKSTRRSIRLPETIDLG	-	7559487	LTP	1.00	-	-	0.31	-	medium
S	117	QKFARKSTRRSIRLPETIDLG	PKC_group	8615792	LTP	1.00	-	-	0.31	-	medium
S	117	QKFARKSTRRSIRLPETIDLG	PKC_alpha	8615792	LTP	1.00	-	-	0.31	-	medium