Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

CD45 (Receptor tyrosine phosphatase)

Seq-ID:

P08575 [Homo sapiens]

Download:

Interaction Network(s):

NetworKIN

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase binding, transmembrane receptor protein tyrosine phosphatase activity	focal adhesion, integral to plasma membrane, membrane raft	positive regulation of B cell proliferation, B cell receptor signaling pathway, regulation of S phase, immunoglobulin biosynthetic process, defense response to virus, protein amino acid dephosphorylation, positive regulation of antigen receptor-mediated signaling pathway, release of sequestered calcium ion into cytosol, negative regulation of T cell mediated cytotoxicity, T cell receptor signaling pathway, negative regulation of protein kinase activity, B cell proliferation, negative regulation of cytokine-mediated signaling pathway

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	995	LKHELEMSKESEHDSDESSDD	-	15302935	HTP	1.00		-	PTPc	0.81	-	medium
S	999	LEMSKESEHDSDESSDDDSDS	CK2_group	10066810	LTP	1.00		-	PTPc	0.90	-	medium
S	999	LEMSKESEHDSDESSDDDSDS	CK2_alpha	10066810	LTP	1.00		-	PTPc	0.90	-	medium
S	1002	SKESEHDSDESSDDDSDSEEP	CK2_group	10066810	LTP	1.00		-	PTPc	0.92	-	medium
S	1002	SKESEHDSDESSDDDSDSEEP	CK2_alpha	10066810	LTP	1.00		-	PTPc	0.92	-	medium
S	1003	KESEHDSDESSDDDSDSEEPS	CK2_group	10066810	LTP	1.00		-	PTPc	0.92	-	medium
S	1003	KESEHDSDESSDDDSDSEEPS	CK2_alpha	10066810	LTP	1.00		-	PTPc	0.92	-	medium
S	1007	HDSDESSDDDSDSEEPSKYIN	CK2_alpha	10066810	LTP	1.00	MOD_CK2_1	-	PTPc	0.81	-	medium
S	1007	HDSDESSDDDSDSEEPSKYIN	PKC_group	9111075	LTP	1.00	MOD_CK2_1	-	PTPc	0.81	-	medium
Y	1216	RPGMVSTFEQYQFLYDVIAST	Csk	7507203	LTP	1.00		Lck SH2	PTPc	0.26	-	medium