Substrate: c-met (Receptor tyrosine kinase for hepatocyte growth factor.)
Seq-ID: P08581 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-18299   RANB9_HUMAN
MINT-58374   GAB1_MOUSE
MINT-58404   GAB1_HUMAN
MINT-6539587   CBL_HUMAN
MINT-6787689   PTN1_HUMAN
MINT-6798640   PTN11_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
hepatocyte growth factor receptor activity,
ATP binding,
protein binding		 integral to plasma membrane,
basal plasma membrane		 protein amino acid phosphorylation,
multicellular organismal development,
cell proliferation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 830 FFMLDGILSKYFDLIYVHNPV - 12746450
LTP
0.16
 - IPT
0.02
 --
T 977 ELVRYDARVHTPHLDRLVSAR - 17192257
HTP
0.18
 - -
0.27
 --
S 985 VHTPHLDRLVSARSVSPTTEM - 7925482
LTP
0.26
 - -
0.44
 --
S 985 VHTPHLDRLVSARSVSPTTEM PKC_delta 15075332
LTP
0.26
 - -
0.44
 --
S 985 VHTPHLDRLVSARSVSPTTEM PKC_epsilon 15075332
LTP
0.26
 - -
0.44
 --
S 985 VHTPHLDRLVSARSVSPTTEM PKC_group 8294430
LTP
0.26
 - -
0.44
 --
S 988 PHLDRLVSARSVSPTTEMVSN - 17192257
HTP
1.00
 - -
0.42
 --
S 988 PHLDRLVSARSVSPTTEMVSN - 18669648
HTP
1.00
 - -
0.42
 --
S 990 LDRLVSARSVSPTTEMVSNES - 17192257
HTP
1.00
 - -
0.41
 --
S 990 LDRLVSARSVSPTTEMVSNES - 18669648
HTP
1.00
 - -
0.41
 --
T 992 RLVSARSVSPTTEMVSNESVD - 18669648
HTP
1.00
 - -
0.40
 --
T 993 LVSARSVSPTTEMVSNESVDY - 18669648
HTP
0.24
 - -
0.40
 --
S 997 RSVSPTTEMVSNESVDYRATF - 18669648
HTP
1.00
 - -
0.45
 --
S 1000 SPTTEMVSNESVDYRATFPED - 18669648
HTP
1.00
 - -
0.45
 --
Y 1003 TEMVSNESVDYRATFPEDQFP - 11741535
LTP
1.00
 CBL SH2 -
0.44
 --
Y 1003 TEMVSNESVDYRATFPEDQFP - 17192257
HTP
1.00
 CBL SH2 -
0.44
 --
Y 1003 TEMVSNESVDYRATFPEDQFP - 18083107
HTP
1.00
 CBL SH2 -
0.44
 --
Y 1230 VADFGLARDMYDKEYYSVHNK Met 12475979
LTP
1.00
 - TyrKc
0.11
 3F66 34.06%
Y 1230 VADFGLARDMYDKEYYSVHNK - 18083107
HTP
1.00
 - TyrKc
0.11
 3F66 34.06%
Y 1234 GLARDMYDKEYYSVHNKTGAK Met 1247597
LTP
1.00
 - TyrKc
0.18
 3F66 31.88%
Y 1234 GLARDMYDKEYYSVHNKTGAK Met 8302603
LTP
1.00
 - TyrKc
0.18
 3F66 31.88%
Y 1234 GLARDMYDKEYYSVHNKTGAK Met 7961992
LTP
1.00
 - TyrKc
0.18
 3F66 31.88%
Y 1234 GLARDMYDKEYYSVHNKTGAK - 18083107
HTP
1.00
 - TyrKc
0.18
 3F66 31.88%
Y 1235 LARDMYDKEYYSVHNKTGAKL - 1247597
LTP
1.00
 - TyrKc
0.18
 3F66 10.48%
Y 1235 LARDMYDKEYYSVHNKTGAKL Met 8302603
LTP
1.00
 - TyrKc
0.18
 3F66 10.48%
Y 1235 LARDMYDKEYYSVHNKTGAKL - 18083107
HTP
1.00
 - TyrKc
0.18
 3F66 10.48%
Y 1313 LQPEYCPDPLYEVMLKCWHPK - 7708691
LTP
0.97
 PIK3R1 SH2;
STAT3 SH2		 TyrKc
0.10
 3F66 15.28%
Y 1313 LQPEYCPDPLYEVMLKCWHPK - 10069803
LTP
0.97
 PIK3R1 SH2;
STAT3 SH2		 TyrKc
0.10
 3F66 15.28%
Y 1349 AIFSTFIGEHYVHVNATYVNV Met 12475979
LTP
1.00
 GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.03
 3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 9444958
LTP
1.00
 GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.03
 3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 9252406
LTP
1.00
 GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.03
 3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 7513258
LTP
1.00
 GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.03
 3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV Met 7731718
LTP
1.00
 GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.03
 3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV Met 7687741
LTP
1.00
 GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.03
 3F66 100.00%
Y 1349 AIFSTFIGEHYVHVNATYVNV - 9826708
LTP
1.00
 GRB2 SH2;
Lck SH2;
PIK3R1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.03
 3F66 100.00%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 12475979
LTP
1.00
 GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.06
 1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 9444958
LTP
1.00
 GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.06
 1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 9252406
LTP
1.00
 GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.06
 1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 7513258
LTP
1.00
 GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.06
 1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP Met 7731718
LTP
1.00
 GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.06
 1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 8662889
LTP
1.00
 GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.06
 1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP Met 7961992
LTP
1.00
 GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.06
 1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP Met 7687741
LTP
1.00
 GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.06
 1R0P 15.72%
Y 1356 GEHYVHVNATYVNVKCVAPYP - 9826708
LTP
1.00
 GRB2 SH2;
INPP5D SH2;
INPPL1 SH2;
PIK3R1 SH2;
PLCG1 SH2;
PLCG_group SH2;
SHC_group SH2;
Src SH2		 -
0.06
 1R0P 15.72%
Y 1365 TYVNVKCVAPYPSLLSSEDNA - 12475979
LTP
1.00
 - -
0.21
 --

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