Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

FGFR-1 (Receptor tyrosine kinase)

Seq-ID:

P11362 [Homo sapiens]

Download:

Interaction Network(s):

NetworKIN

External Source(s):

Phosida

MINT Interaction(s):

MINT-74539 ERBB3_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
heparin binding, fibroblast growth factor receptor activity, ATP binding	extracellular region, membrane fraction, integral to plasma membrane	protein amino acid phosphorylation, MAPKKK cascade, cell growth

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	154	TKPNRMPVAPYWTSPEKMEKK	FGFR1	12601080	LTP	0.25		-	-	0.62	1CVS	50.66%
Y	280	GSNVEFMCKVYSDPQPHIQWL	FGFR1	12601080	LTP	0.83		-	IGc2	0.16	1CVS	51.09%
Y	307	GSKIGPDNLPYVQILKTAGVN	FGFR1	12601080	LTP	0.88		-	IGc2	0.26	1CVS	29.26%
Y	463	GTPMLAGVSEYELPEDPRWEL	-	9880324	LTP	0.65		-	-	0.41	-	-
Y	463	GTPMLAGVSEYELPEDPRWEL	FGFR1	8622701	LTP	0.65		-	-	0.41	-	-
Y	463	GTPMLAGVSEYELPEDPRWEL	-	12601080	LTP	0.65		-	-	0.41	-	-
Y	583	LQARRPPGLEYCYNPSHNPEE	-	9880324	LTP	1.00		-	TyrKc	0.48	-	-
Y	583	LQARRPPGLEYCYNPSHNPEE	FGFR1	8622701	LTP	1.00		-	TyrKc	0.48	-	-
Y	583	LQARRPPGLEYCYNPSHNPEE	-	12601080	LTP	1.00		-	TyrKc	0.48	-	-
Y	585	ARRPPGLEYCYNPSHNPEEQL	-	9880324	LTP	0.61		-	TyrKc	0.51	-	-
Y	585	ARRPPGLEYCYNPSHNPEEQL	FGFR1	8622701	LTP	0.61		-	TyrKc	0.51	-	-
Y	585	ARRPPGLEYCYNPSHNPEEQL	-	12601080	LTP	0.61		-	TyrKc	0.51	-	-
Y	605	LSSKDLVSCAYQVARGMEYLA	FGFR1	12601080	LTP	0.97		-	TyrKc	0.12	1FGK	15.72%
Y	653	GLARDIHHIDYYKKTTNGRLP	-	9880324	LTP	1.00		-	TyrKc	0.20	1FGK	19.21%
Y	653	GLARDIHHIDYYKKTTNGRLP	FGFR1	8622701	LTP	1.00		-	TyrKc	0.20	1FGK	19.21%
Y	653	GLARDIHHIDYYKKTTNGRLP	-	12601080	LTP	1.00		-	TyrKc	0.20	1FGK	19.21%
Y	653	GLARDIHHIDYYKKTTNGRLP	-	18083107	HTP	1.00		-	TyrKc	0.20	1FGK	19.21%
Y	654	LARDIHHIDYYKKTTNGRLPV	-	9880324	LTP	1.00		-	TyrKc	0.20	1FGK	67.69%
Y	654	LARDIHHIDYYKKTTNGRLPV	FGFR1	8622701	LTP	1.00		-	TyrKc	0.20	1FGK	67.69%
Y	654	LARDIHHIDYYKKTTNGRLPV	-	12601080	LTP	1.00		-	TyrKc	0.20	1FGK	67.69%
Y	730	DKPSNCTNELYMMMRDCWHAV	-	9880324	LTP	1.00		-	TyrKc	0.26	1FGK	15.28%
Y	730	DKPSNCTNELYMMMRDCWHAV	FGFR1	8622701	LTP	1.00		-	TyrKc	0.26	1FGK	15.28%
Y	730	DKPSNCTNELYMMMRDCWHAV	-	12601080	LTP	1.00		-	TyrKc	0.26	1FGK	15.28%
Y	766	RIVALTSNQEYLDLSMPLDQY	-	9880324	LTP	0.89		PLCG1 SH2	-	0.29	-	-
Y	766	RIVALTSNQEYLDLSMPLDQY	FGFR1	8622701	LTP	0.89		PLCG1 SH2	-	0.29	-	-