Substrate: FGFR-1 (Receptor tyrosine kinase)
Seq-ID: P11362 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
MINT-74539   ERBB3_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
heparin binding,
fibroblast growth factor receptor activity,
ATP binding		 extracellular region,
membrane fraction,
integral to plasma membrane		 protein amino acid phosphorylation,
MAPKKK cascade,
cell growth
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 154 TKPNRMPVAPYWTSPEKMEKK FGFR1 12601080
LTP
0.25
 - -
0.62
 1CVS 50.66%
Y 280 GSNVEFMCKVYSDPQPHIQWL FGFR1 12601080
LTP
0.83
 - IGc2
0.16
 1CVS 51.09%
Y 307 GSKIGPDNLPYVQILKTAGVN FGFR1 12601080
LTP
0.88
 - IGc2
0.26
 1CVS 29.26%
Y 463 GTPMLAGVSEYELPEDPRWEL - 9880324
LTP
0.65
 - -
0.41
 --
Y 463 GTPMLAGVSEYELPEDPRWEL FGFR1 8622701
LTP
0.65
 - -
0.41
 --
Y 463 GTPMLAGVSEYELPEDPRWEL - 12601080
LTP
0.65
 - -
0.41
 --
Y 583 LQARRPPGLEYCYNPSHNPEE - 9880324
LTP
1.00
 - TyrKc
0.48
 --
Y 583 LQARRPPGLEYCYNPSHNPEE FGFR1 8622701
LTP
1.00
 - TyrKc
0.48
 --
Y 583 LQARRPPGLEYCYNPSHNPEE - 12601080
LTP
1.00
 - TyrKc
0.48
 --
Y 585 ARRPPGLEYCYNPSHNPEEQL - 9880324
LTP
0.61
 - TyrKc
0.51
 --
Y 585 ARRPPGLEYCYNPSHNPEEQL FGFR1 8622701
LTP
0.61
 - TyrKc
0.51
 --
Y 585 ARRPPGLEYCYNPSHNPEEQL - 12601080
LTP
0.61
 - TyrKc
0.51
 --
Y 605 LSSKDLVSCAYQVARGMEYLA FGFR1 12601080
LTP
0.97
 - TyrKc
0.12
 1FGK 15.72%
Y 653 GLARDIHHIDYYKKTTNGRLP - 9880324
LTP
1.00
 - TyrKc
0.20
 1FGK 19.21%
Y 653 GLARDIHHIDYYKKTTNGRLP FGFR1 8622701
LTP
1.00
 - TyrKc
0.20
 1FGK 19.21%
Y 653 GLARDIHHIDYYKKTTNGRLP - 12601080
LTP
1.00
 - TyrKc
0.20
 1FGK 19.21%
Y 653 GLARDIHHIDYYKKTTNGRLP - 18083107
HTP
1.00
 - TyrKc
0.20
 1FGK 19.21%
Y 654 LARDIHHIDYYKKTTNGRLPV - 9880324
LTP
1.00
 - TyrKc
0.20
 1FGK 67.69%
Y 654 LARDIHHIDYYKKTTNGRLPV FGFR1 8622701
LTP
1.00
 - TyrKc
0.20
 1FGK 67.69%
Y 654 LARDIHHIDYYKKTTNGRLPV - 12601080
LTP
1.00
 - TyrKc
0.20
 1FGK 67.69%
Y 730 DKPSNCTNELYMMMRDCWHAV - 9880324
LTP
1.00
 - TyrKc
0.26
 1FGK 15.28%
Y 730 DKPSNCTNELYMMMRDCWHAV FGFR1 8622701
LTP
1.00
 - TyrKc
0.26
 1FGK 15.28%
Y 730 DKPSNCTNELYMMMRDCWHAV - 12601080
LTP
1.00
 - TyrKc
0.26
 1FGK 15.28%
Y 766 RIVALTSNQEYLDLSMPLDQY - 9880324
LTP
0.89
 PLCG1 SH2 -
0.29
 --
Y 766 RIVALTSNQEYLDLSMPLDQY FGFR1 8622701
LTP
0.89
 PLCG1 SH2 -
0.29
 --

Substrate: FGFR-1 (Receptor tyrosine kinase)
Seq-ID: P16092 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
fibroblast growth factor binding,
heparin binding,
fibroblast growth factor receptor activity,
ATP binding		 integral to membrane mesenchymal cell differentiation,
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway,
positive regulation of mesenchymal cell proliferation,
protein amino acid phosphorylation,
branching involved in salivary gland morphogenesis,
negative regulation of apoptosis,
ureteric bud development,
angiogenesis,
positive regulation of cardiac muscle cell proliferation,
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling,
midbrain development,
in utero embryonic development,
cell maturation,
inner ear morphogenesis,
regulation of lateral mesodermal cell fate specification,
lung-associated mesenchyme development,
negative regulation of gene expression,
induction of an organ,
paraxial mesoderm development,
embryonic limb morphogenesis,
chondrocyte differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 766 RIVALTSNQEYLDLSIPLDQY - 12181353
LTP
0.91
 - -
0.24
 --

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