Substrate: Vav (Adaptor molecule. GDP/GTP exchange factor in Rho/Rac molecule)
Seq-ID: P15498 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-17467   CRK_HUMAN
MINT-2837376   PLCG1_BOVIN
MINT-4549720   3BP2_HUMAN
MINT-6743318   RAC1_HUMAN
MINT-6743347   RHOA_HUMAN
MINT-6743356   CDC42_HUMAN
MINT-7226634   ITB2_HUMAN
MINT-7226674   ABL1_HUMAN
MINT-7300569   KHDR1_MOUSE
MINT-7300587   KHDR1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Rho guanyl-nucleotide exchange factor activity,
metal ion binding,
sequence-specific DNA binding transcription factor activity,
protein binding		 plasma membrane,
cytosol		 induction of apoptosis by extracellular signals,
apoptosis,
regulation of Rho protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 142 EEESVGDEDIYSGLSDQIDDT Lck 16285729
LTP
1.00
 Lck SH2 -
0.49
 - medium
Y 160 DDTVEEDEDLYDCVENEEAEG Lck 16285729
LTP
1.00
 - -
0.51
 - medium
Y 160 DDTVEEDEDLYDCVENEEAEG - 15699036
LTP
1.00
 - -
0.51
 - medium
Y 174 ENEEAEGDEIYEDLMRSEPVS - 898671
LTP
1.00
 Fyn SH2;
PTPN6 SH2		 -
0.54
 - medium
Y 174 ENEEAEGDEIYEDLMRSEPVS - 10669745
LTP
1.00
 Fyn SH2;
PTPN6 SH2		 -
0.54
 - medium
Y 844 ANYVEEDYSEYC          - 16497976
HTP
0.00
 - -
0.09
 - medium

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