Substrate: Tyk2 (Cytoplasmic tyrosine kinase)
Seq-ID: P29597 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-73134   INAR1_HUMAN
MINT-4507312   KPCA_HUMAN
MINT-6793782   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Janus kinase activity,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
growth hormone receptor binding		 cytoplasm,
cytoskeleton,
nucleus,
membrane		 peptidyl-tyrosine phosphorylation,
intracellular protein kinase cascade
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 292 LLAQAEGEPCYIRDSGVAPTD - 15659558
HTP
0.24
 - -
0.44
 - medium
Y 292 LLAQAEGEPCYIRDSGVAPTD - 18083107
HTP
0.24
 - -
0.44
 - medium
Y 1054 LAKAVPEGHEYYRVREDGDSP Tyk2 8702790
LTP
1.00
 - TyrKc
0.26
 - medium
Y 1054 LAKAVPEGHEYYRVREDGDSP JAK1 8702790
LTP
1.00
 - TyrKc
0.26
 - medium
Y 1054 LAKAVPEGHEYYRVREDGDSP - 15659558
LTP
1.00
 - TyrKc
0.26
 - medium
Y 1054 LAKAVPEGHEYYRVREDGDSP - 15659558
HTP
1.00
 - TyrKc
0.26
 - medium
Y 1055 AKAVPEGHEYYRVREDGDSPV Tyk2 8702790
LTP
1.00
 - TyrKc
0.24
 - medium
Y 1055 AKAVPEGHEYYRVREDGDSPV JAK1 8702790
LTP
1.00
 - TyrKc
0.24
 - medium
Y 1055 AKAVPEGHEYYRVREDGDSPV - 15659558
LTP
1.00
 - TyrKc
0.24
 - medium
Y 1055 AKAVPEGHEYYRVREDGDSPV - 15659558
HTP
1.00
 - TyrKc
0.24
 - medium

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