Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Tyk2 (Cytoplasmic tyrosine kinase)

Seq-ID:

P29597 [Homo sapiens]

Download:

Interaction Network(s):

STRING

NetworKIN

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-73134   INAR1_HUMAN
MINT-4507312   KPCA_HUMAN
MINT-6793782   PTN1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Janus kinase activity, non-membrane spanning protein tyrosine kinase activity, ATP binding, growth hormone receptor binding	cytoplasm, cytoskeleton, nucleus, membrane	peptidyl-tyrosine phosphorylation, intracellular protein kinase cascade

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	292	LLAQAEGEPCYIRDSGVAPTD	-	15659558	HTP	0.24		-	-	0.44	-	medium
Y	292	LLAQAEGEPCYIRDSGVAPTD	-	18083107	HTP	0.24		-	-	0.44	-	medium
Y	1054	LAKAVPEGHEYYRVREDGDSP	Tyk2	8702790	LTP	1.00		-	TyrKc	0.26	-	medium
Y	1054	LAKAVPEGHEYYRVREDGDSP	JAK1	8702790	LTP	1.00		-	TyrKc	0.26	-	medium
Y	1054	LAKAVPEGHEYYRVREDGDSP	-	15659558	LTP	1.00		-	TyrKc	0.26	-	medium
Y	1054	LAKAVPEGHEYYRVREDGDSP	-	15659558	HTP	1.00		-	TyrKc	0.26	-	medium
Y	1055	AKAVPEGHEYYRVREDGDSPV	Tyk2	8702790	LTP	1.00		-	TyrKc	0.24	-	medium
Y	1055	AKAVPEGHEYYRVREDGDSPV	JAK1	8702790	LTP	1.00		-	TyrKc	0.24	-	medium
Y	1055	AKAVPEGHEYYRVREDGDSPV	-	15659558	LTP	1.00		-	TyrKc	0.24	-	medium
Y	1055	AKAVPEGHEYYRVREDGDSPV	-	15659558	HTP	1.00		-	TyrKc	0.24	-	medium

Tyk2 (Cytoplasmic tyrosine kinase)

Seq-ID:

Q9R117 [Mus musculus]

Download:

Interaction Network(s):

-

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
Janus kinase activity, non-membrane spanning protein tyrosine kinase activity, ATP binding	cytoskeleton, membrane	peptidyl-tyrosine phosphorylation, intracellular protein kinase cascade

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1047	LAKAVPEGHEYYRVREDGDSP	-	14996842	LTP	1.00		-	TyrKc	0.27	-	low
Y	1048	AKAVPEGHEYYRVREDGDSPV	-	14996842	LTP	1.00		-	TyrKc	0.25	-	low