Substrate: PKB-alpha (RAC-alpha serine/threonine kinase (EC 2.7.1.-) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT))
Seq-ID: P31750 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-4049581   PDE3A_MOUSE
MINT-6175057   STK4_HUMAN
MINT-6793722   PTN1_HUMAN
MINT-6978911   HS90A_MOUSE
MINT-6978941   UBIQ_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
ATP binding		 plasma membrane,
spindle,
cytosol,
lamellipodium,
nucleus		 response to food,
glycogen cell development involved in embryonic placenta development,
protein ubiquitination,
regulation of neuron projection development,
maternal placenta development,
glycogen biosynthetic process,
apoptotic mitochondrial changes,
germ cell development,
inflammatory response,
insulin-like growth factor receptor signaling pathway,
peptidyl-serine phosphorylation,
positive regulation of proteasomal ubiquitin-dependent protein catabolic process,
anagen,
positive regulation of sodium ion transport,
regulation of translation,
labyrinthine layer blood vessel development,
protein catabolic process,
protein kinase B signaling cascade,
glucose transport,
insulin receptor signaling pathway,
regulation of survival gene product expression
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 124 EEETMDFRSGSPSDNSGAEEM - 17242355
HTP
0.89
 - -
0.72
 - medium
S 126 ETMDFRSGSPSDNSGAEEMEV - 17242355
HTP
0.42
 - -
0.65
 - medium
S 129 DFRSGSPSDNSGAEEMEVSLA - 17242355
HTP
0.53
 - -
0.62
 - medium
T 308 EGIKDGATMKTFCGTPEYLAP - 15364915
LTP
1.00
 - S_TKc
0.22
 - medium
T 308 EGIKDGATMKTFCGTPEYLAP PDK-1 12682057
LTP
1.00
 - S_TKc
0.22
 - medium
T 308 EGIKDGATMKTFCGTPEYLAP - 11087733
LTP
1.00
 - S_TKc
0.22
 - medium
T 308 EGIKDGATMKTFCGTPEYLAP PDK-1 19047061
LTP
1.00
 - S_TKc
0.22
 - medium
T 308 EGIKDGATMKTFCGTPEYLAP - 17141160
LTP
1.00
 - S_TKc
0.22
 - medium
Y 315 TMKTFCGTPEYLAPEVLEDND SRC 11445557
LTP
1.00
 - S_TKc
0.25
 - medium
Y 326 LAPEVLEDNDYGRAVDWWGLG SRC 11445557
LTP
1.00
 - S_TKc
0.10
 - medium
S 473 SERRPHFPQFSYSASGTA    mTOR 16221682
LTP
0.95
 - S_TK_X
0.53
 - medium
S 473 SERRPHFPQFSYSASGTA    - 15364915
LTP
0.95
 - S_TK_X
0.53
 - medium
S 473 SERRPHFPQFSYSASGTA    - 17141160
LTP
0.95
 - S_TK_X
0.53
 - medium

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