Substrate: MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1))
Seq-ID: P31938 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
MINT-16657   BRAF_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
MAP kinase kinase activity,
ATP binding,
protein tyrosine kinase activity,
receptor signaling protein tyrosine phosphatase activity		 placenta blood vessel development,
positive regulation of cell differentiation,
cell motility,
keratinocyte differentiation,
labyrinthine layer development,
activation of MAPK activity
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 218 DFGVSGQLIDSMANSFVGTRS - 15665076
LTP
1.00
 - S_TKc
0.19
 3EQC 29.51%
S 218 DFGVSGQLIDSMANSFVGTRS - 14963034
LTP
1.00
 - S_TKc
0.19
 3EQC 29.51%
S 218 DFGVSGQLIDSMANSFVGTRS - 12181353
LTP
1.00
 - S_TKc
0.19
 3EQC 29.51%
S 218 DFGVSGQLIDSMANSFVGTRS - 12032835
LTP
1.00
 - S_TKc
0.19
 3EQC 29.51%
S 218 DFGVSGQLIDSMANSFVGTRS - 12604616
LTP
1.00
 - S_TKc
0.19
 3EQC 29.51%
S 222 SGQLIDSMANSFVGTRSYMSP - 15665076
LTP
1.00
 - S_TKc
0.28
 --
S 222 SGQLIDSMANSFVGTRSYMSP - 14963034
LTP
1.00
 - S_TKc
0.28
 --
S 222 SGQLIDSMANSFVGTRSYMSP - 12181353
LTP
1.00
 - S_TKc
0.28
 --
S 222 SGQLIDSMANSFVGTRSYMSP - 12032835
LTP
1.00
 - S_TKc
0.28
 --
S 222 SGQLIDSMANSFVGTRSYMSP - 12604616
LTP
1.00
 - S_TKc
0.28
 --
T 286 GCHVEGDAAETPPRPRTPGRP CDK5 11684694
LTP
0.12
 MOD_CDK_SPxK_1
 - S_TKc
0.70
 --
T 286 GCHVEGDAAETPPRPRTPGRP CDK5 15665076
LTP
0.12
 MOD_CDK_SPxK_1
 - S_TKc
0.70
 --
T 292 DAAETPPRPRTPGRPLSSYGM MAP3K1 8019005
LTP
0.12
 - S_TKc
0.78
 --

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