Substrate: Ptpn11 (Protein-tyrosine phosphatase, non-receptor type 11)
Seq-ID: P35235 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-7258938   FAK1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein tyrosine phosphatase activity,
peptide hormone receptor binding		 reproductive process in a multicellular organism,
regulation of protein export from nucleus,
glucose homeostasis,
regulation of multicellular organism growth,
nerve growth factor receptor signaling pathway,
negative regulation of cortisol secretion,
positive regulation of signal transduction,
DNA damage checkpoint,
positive regulation of hormone secretion,
negative regulation of growth hormone secretion,
activation of MAPK activity,
axonogenesis,
negative regulation of insulin secretion,
triglyceride metabolic process,
organ growth,
hormone metabolic process,
hormone-mediated signaling pathway
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 62 THIKIQNTGDYYDLYGGEKFA - 15592455
HTP
0.97
 - SH2
0.25
 2SHP 9.61%
Y 304 DGDPNEPVSDYINANIIMPEF - 8995399
LTP
1.00
 - PTPc
0.45
 3B7O 0.44%
Y 327 KCNNSKPKKSYIATQGCLQNT - 8995399
LTP
1.00
 - PTPc
0.42
 3B7O 2.62%
Y 546 EQKSKRKGHEYTNIKYSLVDQ - 12923167
LTP
1.00
 - -
0.47
 --
Y 584 AEMREDSARVYENVGLMQQQR - 12522270
HTP
0.82
 - -
0.51
 --

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