Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Caveolin-1 (May act as a scaffolding protein within the caveolar membranes )

Seq-ID:

P49817 [Mus musculus]

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Interaction Network(s):

External Source(s):

MINT Interaction(s):

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GO-Terms:

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Molecular Function	Cellular Component	Biological Process
peptidase activator activity	caveola, integral to membrane of membrane fraction, integral to plasma membrane, perinuclear region of cytoplasm, protein complex, cell cortex, endoplasmic reticulum, Golgi membrane	negative regulation of gene-specific transcription from RNA polymerase II promoter, positive regulation of vasoconstriction, inactivation of MAPK activity, negative regulation of tyrosine phosphorylation of Stat5 protein, cholesterol homeostasis, positive regulation of calcium ion transport into cytosol, lipid storage, mammary gland involution, vasoconstriction, negative regulation of nitric oxide biosynthetic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of epithelial cell differentiation, positive regulation of metalloenzyme activity, response to calcium ion, negative regulation of MAPKKK cascade, lactation, vasculogenesis, calcium ion transport, skeletal muscle tissue development, T cell costimulation, triglyceride metabolic process, protein homooligomerization, negative regulation of endothelial cell proliferation, nitric oxide homeostasis, endocytosis, negative regulation of cytokine-mediated signaling pathway, regulation of smooth muscle contraction, membrane depolarization, regulation of fatty acid metabolic process, response to hypoxia, response to estrogen stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	14	GKYVDSEGHLYTVPIREQGNI	-	12036959	LTP	-	GRB7 SH2	Caveolin	0.30	-	low
Y	14	GKYVDSEGHLYTVPIREQGNI	Abl	11075810	LTP	-	GRB7 SH2	Caveolin	0.30	-	low
Y	14	GKYVDSEGHLYTVPIREQGNI	SRC	11075810	LTP	-	GRB7 SH2	Caveolin	0.30	-	low
Y	14	GKYVDSEGHLYTVPIREQGNI	SRC	8632005	LTP	-	GRB7 SH2	Caveolin	0.30	-	low
Y	14	GKYVDSEGHLYTVPIREQGNI	Abl	12531427	LTP	-	GRB7 SH2	Caveolin	0.30	-	low
Y	14	GKYVDSEGHLYTVPIREQGNI	-	11094059	LTP	-	GRB7 SH2	Caveolin	0.30	-	low
Y	14	GKYVDSEGHLYTVPIREQGNI	-	15592455	HTP	-	GRB7 SH2	Caveolin	0.30	-	low