Substrate: EGFR (Receptor for EGF and other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor,)
Seq-ID: Q01279 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-49967   EPS15_MOUSE
MINT-60748   DOK2_MOUSE
MINT-6765439   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
epidermal growth factor receptor activity,
receptor signaling protein tyrosine kinase activity,
ATP binding		 basolateral plasma membrane,
integral to membrane,
endocytic vesicle		 cerebral cortex cell migration,
hair follicle development,
embryonic placenta development,
protein amino acid autophosphorylation,
positive regulation of epithelial cell proliferation,
digestive tract morphogenesis,
regulation of peptidyl-tyrosine phosphorylation,
salivary gland morphogenesis,
morphogenesis of an epithelial fold
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 270 CKDTCPPLMLYNPTTYQMDVN - 15016810
LTP
1.00
 - FU
0.17
 --
Y 316 SCVRACGPDYYEVEEDGIRKC - 15378723
HTP
0.13
 - Furin-like
0.07
 --
Y 871 AKLLGAEEKEYHAEGGKVPIK - 14647453
LTP
1.00
 - TyrKc
0.18
 2EB2 17.03%
Y 1018 DMEDVVDADEYLIPQQGFFNS - 16123117
LTP
1.00
 - -
0.41
 1XKK 41.92%
Y 1069 RVKEDAFLQRYSSDPTGAVTE EGFR 10635327
LTP
1.00
 - -
0.54
 --
Y 1092 IDDAFLPVPEYVNQSVPKRPA - 16123117
LTP
0.12
 - -
0.55
 --
Y 1172 SHQMSLDNPDYQQDFFPKETK - 16902180
LTP
1.00
 - -
0.74
 --
Y 1197 FKGPTAENAEYLRVAPPSSEF - 12527890
LTP
1.00
 - -
0.55
 --

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