Substrate: Notch2 (Cell surface receptor)
Seq-ID: Q04721 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-61989   SMAD1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor activity,
calcium ion binding,
ligand-regulated transcription factor activity,
protein binding		 integral to plasma membrane,
cell surface,
nucleus		 nervous system development,
transcription,
negative regulation of cell proliferation,
anti-apoptosis,
cell cycle arrest,
cell growth,
positive regulation of Ras protein signal transduction,
hemopoiesis,
stem cell maintenance,
Notch signaling pathway,
regulation of transcription, DNA-dependent,
cell fate determination,
induction of apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 1716 HGSLWLPEGFTLRRDASNHKR - 18669648
HTP
0.00
 - -
0.42
 - medium
S 1778 KVKAEDEALLSEEDDPIDRRP - 18669648
HTP
0.44
 - -
0.64
 - medium
T 1802 QHLEAADIRRTPSLALTPPQA - 18669648
HTP
0.12
 - -
0.72
 - medium
S 1804 LEAADIRRTPSLALTPPQAEQ - 18669648
HTP
0.23
 - -
0.73
 - medium
T 1808 DIRRTPSLALTPPQAEQEVDV - 15302935
HTP
1.00
 - -
0.71
 - medium
T 1808 DIRRTPSLALTPPQAEQEVDV - 18669648
HTP
1.00
 - -
0.71
 - medium
S 1841 PLMLASLRGGSSDLSDEDEDA - 18669648
HTP
0.06
 - ANK
0.67
 - medium
S 1845 ASLRGGSSDLSDEDEDAEDSS - 18669648
HTP
0.02
 - ANK
0.76
 - medium
S 2070 RLLDEYNVTPSPPGTVLTSAL - 15302935
HTP
1.00
 - -
0.49
 - medium
S 2070 RLLDEYNVTPSPPGTVLTSAL - 18669648
HTP
1.00
 - -
0.49
 - medium
T 2074 EYNVTPSPPGTVLTSALSPVI - 18669648
HTP
0.07
 - -
0.52
 - medium
S 2081 PPGTVLTSALSPVICGPNRSF - 18669648
HTP
0.29
 - -
0.46
 - medium
T 2097 PNRSFLSLKHTPMGKKSRRPS - 18669648
HTP
0.16
 - -
0.70
 - medium
T 2296 SRPPEGKHITTPREPLPPIVT - 18669648
HTP
0.01
 - -
0.79
 - medium

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